Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for AIMP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9255
Official gene symbolAIMP1
Full nameaminoacyl tRNA synthetase complex-interacting multifunctional protein 1
Aliases,EMAP2,EMAPII,SCYE1,p43,
Gene summaryThe protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q24
Gene position107236767 - 107270382  Map Viewer
Gene orientationplus
Gene size33616 bp
Gene sequence
OMIM ID603605