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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYTH3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9265
Official gene symbolCYTH3
Full namecytohesin 3
Aliases,ARNO3,GRP1,PSCD3,
Gene summaryThis gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq]
LocationChromosome: 7   Locus: 7p22.1
Gene position6312242 - 6201410  Map Viewer
Gene orientationminus
Gene size110833 bp
Gene sequence
OMIM ID605081