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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYTH2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9266
Official gene symbolCYTH2
Full namecytohesin 2
Aliases,ARNO,CTS18,CTS18.1,PSCD2,PSCD2L,SEC7L,Sec7p-L,Sec7p-like,
Gene summaryThe protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 19   Locus: 19q13.33
Gene position48972465 - 48985571  Map Viewer
Gene orientationplus
Gene size13107 bp
Gene sequence
OMIM ID602488