Entrez gene ID | | 9289 |
Official gene symbol | | GPR56 |
Full name | | G protein-coupled receptor 56 |
Aliases | | ,BFPP,DKFZp781L1398,TM7LN4,TM7XN1, |
Gene summary | | This gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16q12.2-q21 |
Gene position | | 57653910 - 57698944 Map Viewer |
Gene orientation | | plus |
Gene size | | 45035 bp |
Gene sequence |
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OMIM ID | | 604110 |