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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GPR56 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9289
Official gene symbolGPR56
Full nameG protein-coupled receptor 56
Aliases,BFPP,DKFZp781L1398,TM7LN4,TM7XN1,
Gene summaryThis gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q12.2-q21
Gene position57653910 - 57698944  Map Viewer
Gene orientationplus
Gene size45035 bp
Gene sequence
OMIM ID604110