Entrez gene ID | | 9306 |
Official gene symbol | | SOCS6 |
Full name | | suppressor of cytokine signaling 6 |
Aliases | | ,CIS4,HSPC060,SOCS4,SSI4,STAI4,STATI4, |
Gene summary | | The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq] |
Location | | Chromosome: 18 Locus: 18q22.2 |
Gene position | | 67956137 - 67997434 Map Viewer |
Gene orientation | | plus |
Gene size | | 41298 bp |
Gene sequence |
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OMIM ID | | 605118 |