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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CD27 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 939 Official gene symbol CD27 Full name CD27 molecule Aliases ,MGC20393,S152,T14,TNFRSF7,Tp55, Gene summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq] Location Chromosome: 12   Locus: 12p13 Gene position 6554051 - 6560884  Map Viewer Gene orientation plus Gene size 6834 bp Gene sequence >CD27:6494051..6500884:Length=6834 CGGAAGGGGAAGGGGGTGGAGGTTGCTGCTATGAGAGAGAAAAAAAAAACAGCCACAATA GAGATTCTGCCTTCAAAGGTTGGCTTGCCACCTGAAGCAGCCACTGCCCAGGGGGTGCAA AGAAGAGACAGCAGCGCCCAGCTTGGAGGTGCTAACTCCAGAGGCCAGCATCAGCAACTG GGCACAGAAAGGAGCCGCCTGGGCAGGGACCATGGCACGGCCACATCCCTGGTGGCTGTG CGTTCTGGGGACCCTGGTGGGGCTCTCAGCTACTCCAGCCCCCAAGAGCTGCCCAGAGAG GCACTACTGGGCTCAGGGAAAGCTGTGCTGCCAGATGTGTGAGCCAGGTAAGAGGGGGCC TTGGTAAGGGCCAGGTGAGTGGCGAAAGAGAGAGGACTGGGGTTAATACAGTAAATAGGC GCAGGGTGAGACTGAGCTCAAGCAAGGAGGGAAATCCTGCAGCTGTGGGGAGGCACCACC TTGAAGAGGGCAGAGAACCAGCCCTTCTCAGGCCTTGATCCCTTACCCTCTCCTCCCAGG AACATTCCTCGTGAAGGACTGTGACCAGCATAGAAAGGCTGCTCAGTGTGATCCTTGCAT ACCGGGGGTCTCCTTCTCTCCTGACCACCACACCCGGCCCCACTGTGAGAGCTGTCGGCA CTGTAACTCTGGTGAGGTGGGCAAGGGTGTGTAGGTGGGGACGATGGACAAGCATCTGGG GGAGCAAGGCTGGTGACGGGTTTGGGGGTGCAAGGAGGATGACGGGGCCAAAGCTTTGGC CTTCTTCAAGGCTCACAGCAAGTGGAGCCAATGCTGGGAAATGCGGCACCCTAGGTGGGG CATGAATTAACGTGGGCAGACATCTAGTATTCCAGGAAAGGGATAAATAGAATTTGAGGG ATTGGTGAGAACGGGTCTATGGATAGGATCAAGACAATAAAATGAGAGAAGTGGCTCTAT GACCCCAGATTTCGGGCAAGCAACCCCCAACCAATAAACTGACTGTGTTCCCAGAGTGCA CATGTGCAGGTTGGCCATTGGGAATTTGGAATACATCTTTCTAAGGAAATAACAAAGCAA CCCAATAGGTAACAACCTTTTTTTGCACAAAAGCCAATTTGAGAAAATGAGTATGTATGT AGCCTGTGTTTTTATTTTATAGTTCCAAAAAAAAAGGTTTTTTTTAAACTAAGAAGTATA ATATCTGCAGTTGTGCTTATGAATGCTGTTATTATTTCTCCATCTTCGCTACAATTTCAG AAACTACGGCCAGTATACACTAGAATAGCAGGCTTTAAAGTGGCCCCTTTGAACAAATGT TCTCTAGCAAGACACTTTTTAGAACCAGGTAACTGTAACTATTAAACTACCTACTTGCAA AACGTGTTTGGTGTCACTGGGTCTCTTGGTACTGGGTTTTGTTTTGTTTAGTTTAGAGAC AAGGTCTAGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCAATCATAGCTCCCCACAGCC TTGAACTCCTGGGCTCAAGCAATCTTCTAGTCTCAGCCTCTGAAAGTGCCAGGATTACAG GTGTGAGCTGTAGTGCCTGGTCCCGTAAAAACAAAAACAAAAACCAACACCAGATGTGGT GGCTCATGCCTATAATCCCAGCACTTGGGAGGCCAAGGCAGAAGGGTATTTGCATATTTT GTAGAGACTTGAGCCCAGGAGCTTGAGACCAGCTGGGCAACATAGTGAGACCTTGTCTCT AAAAAAATTGGCTGGTCATGGTAGTGCACCTGCAGTCCCAGCTACTTGGGAGGCTGAGAT GGGAAGATCACTTGAGCCCAAGAGGTCCCCAAGAGGTCCAGGCTGCTCACATCACTGCAC TCCAGCCTGGGTAACAGAGCAAAACCCTTTTTCACACACACACACACACACACACAAAAA GCCAGAGCAGTGGCTCACACTTGTAATCCCAGCACTTTAGGAGGCCAAGGCAGGCGGATC CCTTGAGCCCAGGAGTTTAAGAACACCCTGGGCAACATGGCAAAACCCTGTCTCTACTAA AAATACAAAAAGTTAGCCAGGCGTGGTGGCACGAACCTGTAGTCCCAGCTACTCAGAAGG CTGAAGTGAGAAGATCACTTGAGTCCAGGAAGTGGAGGCTGCAGTGAGCCGTGACTGTAC CACTGCACTCCAGCTTGGGAGACAGAGTGAGCAGAGTGAGACCCTGTTTCCAAAAAAAAA AAGAAAACAAAAGCTTTTCCATTGCAAATCAACCAAAAAGGAACGTCTTTAATACACAAG AAATATTCTTCAGTCTACTTAACTTAAAAATGTAACTGTAATAGATGCTTTTCTCTTGAC AGCGGCCCCGGCAGGGTTGGAACTTTTCCTAGTCAAAACCCCCCTACTCACTCTGCAGAC CCTTCCTGAAGGTCTTCGCCCCATACTGAGCCCATCTTCAGTCCCTTCACTTGTTCCAAA CTAGCCCAATCCATGACCCTTCTCTGGGAGCTCAGCCAATAGATCCCAAAGTACCACAGC AGCACCTGGCTGCAGAAGGACCCCCGGGAAATGCAGTCAGGGGTGAGAAGATGGGTGGGC TGAATGAGCTCGGCCCTCTCTGGGCCTTAGTGCTGGCATCTATGAGATGAGGACATGCCT GAAGTCAGCCTGGAATTTTGAGCCCAGGTTATACCTGGTAAATAGAACTCCCAGGTCTCC GGATACTCACCACTAAAACAATAGCACCTCATTGTTTTTGTTTTGTTTTGTTTTGTTTTT TAATTATACTTTAAGTTCTAGGGTACATGTACACAATGTGCAGGTTTGTTACATAGGTAT ACATGTGCCATGTTGGTGTGCTGCACCCATTAACTCATCATTTACATTAGGTATATCTCC TAATGCTATCCCTCCTCCCTCCCCACACCCCACGACAGGCCCCAGTGTGTGATGTTCCCC TTCCTGTGTCCAAGTGTTCTCATTGTTCAATTCCCACCTACGAGTGAGAACACATTGTTT TTAACCCTCCCCAGCAGCTTCTTTAACCCCTCCATTTCCCTTTTGGCGGAGACCCTTGTC ATCACTCCTCTCTACCACCAGTGCTCTCCCCTCCTGCACTGTCCCAGGCTTCCTCATTCT TCCCTTGCAGGTCCTTATCCAACATGGCTCACAATTCCTGGGAAGCCACAAGGAAACCAA ATTCTAGTAGCAACTCAGAGTCAGCATTCATTAGCAGGTCACAGGGCCATAAGGATGCCA AGAAGGAATTTGTCCCTCTCCTTGTCCTGACAAAAGGCATAAGTAGAAGAAAATTGTTAG GTTTGGTTATGACCTTTGACATTCTCTCTTTGACATCCTCCCTTTCTGCACCCCTCTTCC ACCTGTCAGGGCACCTAGGGCTCCCCGGGTCCCCACAAGTGTCTGCCCTAAGGCCCACCA GGCTTTCTTGCAGCCTGTCCCACATCTGGGTGTCACTGCCTTCCTCTGAATCACCCTCCT CTCAAACCAGCCGCCAGCGAGCCCAGCCCAGCCCAGCTAGTGCCCTACCACACCCGCCCC CAGGATAATTAACACCCAGCCACCCAGCATCGGACCTCTACACTTGAGCAAAATGTATAT TTTAAAGGCAAATTCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGAT CACGAGGTCAGGAGATTGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAA AATACAAAAAATTAGCCAGGTGTGGTGGCACACACCTGTAATCCCAGCTACTAGGGAGGC TGAGGCAGGAGAATCACTTGAACTCAGGAGGCGGAGGTTGCACTGAGCCGAGATCGTGCC ACTGCACTCCAACCTGGGCGACAAAGCAAGACTCTGTCAAAAAACAAACAAACAAAATAA AGGCTAAGTAACTGTAATCAAGTAACTATTTATTATTTATTTATTTTAGTGTATCCACAG GTTGTGCAGCCATCAACACTATCTAATTCTATAACATTTTCGTTACCCCAGAGAAACTTG TACCCCTTAGCAATGACTCCCCATTTCTTCCCCCCAACCAACCCCAGCCCCAGCCCCAGC CCCTGGGAATCCCTAATATACTTTGTTTTGTTTTTTGTTGGTGGTGTTTGAGACAGGATC TCACTCTGTCACCCAGGCTGGAGCGCAGTATCATGATCTCAGCTCACTGTAACCTCCACC TCCCGGGCTCAAGCGATCCTCCCACCTCAGCCTCCCCAGTAGCTTGGGCCTACAGGTGTG CACCACCACACCCAGCTAATTTTTGTATTTTTTGTAGAGACGGGGTTTCACCATGTTGGC CAGGCTGGTCTCAAACTCCTGAGCTCAAGCAATCCACCCACCTCAACCTCCCAAAGTGCT GGGATTACAGGCGTAAGCCACTGCACCTGGCTATTTTCTTTCTTTCTTTTCTTTTTTTTT TTTTTTTGAGACGGAGTTTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGG CTCACTGCAACTTCCACCTCCCGGGTTCAAGCAATTCCCTGCCTCACCCGGCTATTTTAT ATTTGTTGATCTGCTGCTGGTTATGCCTGTGAGCCAAATTTGTACAAATTCTTAAGCTTT ACAATCATGCGTGCCTCTCTGTACGTATATTATACTTTAATTAAAAGTTATTAAAGTATT GGGGCCGAGCACAGTGGCTCACGCCTGTAATCCCAACACTTTGGGAGGCTGAGGCTGGTG CATCACCTGAGGTCAGGAGTTTAATACCAGCCTGGCCAATACAGTAAAACCCCGTCTCTA CTAAAAATACAAAAAATTAGCCGGGTGTGGTGGCACACACCTGTAATCCCAGCTACTTGG GAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAACGAGCCAAGGTC ACGCCATTGCACTCCAGCCTCGGCAACAAGAGCGAGACTCCATCTCAAAAAAATAAATAA AAAATAAAAAATGTATCAGGGAGTACAAGAGAAAGTCATATAAGCTCTTTCTACTTTTCA TGGTTTCTATGTCTGAACCCATGAATCTTCCTTCTGAAAGGTCCAACTTTCTTCTTTAAT AACAATAATAATGGCAAAGGCATTGGGGGACCGTGAGCAAAGGGCAGGCCTTTGCAGGGG TGGGAATGGAAAGGGAAGCACGTCCCTAGAGGTGGGCCTGGGATGGGGGTTGGGGGATGA AGCAAGTGGACCTTGAAGGTCTCCACAGGTCTGAGTGTCCTATGCTCCCTGGGCCTCTCT TCCCCCAGGTCTTCTCGTTCGCAACTGCACCATCACTGCCAATGCTGAGTGTGCCTGTCG CAATGGCTGGCAGTGCAGGGACAAGGAGTGCACCGAGTGTGATCCTCTTCCAAACCCTTC GCTGACCGCTCGGTCGTCTCAGGCCCTGAGCCCACACCCTCAGCCCACCCACTTACCTTA TGTCAGTGGTAAGTTCCAGGCAACTCTCTGTGCCATCACGTGGGGTAGCGGTGATACCCC AACCAGTACTCCCCACTCCTACCCCTAGATAAGGTCAGCCTGTTTCTGCCTTCCCATCCC ATCCAGCACCTCTCAGGCCTTCAGATGTGCCCTATGGGGTCCCCTGCTGCTACTCATTCT GTCTCTGTTTTTCCAGAGATGCTGGAGGCCAGGACAGCTGGGCACATGCAGACTCTGGCT GACTTCAGGCAGCTGCCTGCCCGGACTCTCTCTACCCACTGGCCACGTGAGTTTTCTCCT TAATCCCCACCGCTAGAGAGAATGCATACACGAGGGGCCAGGAGGGAAGCCAGACAGAAA GCTCCTAGGATTAGGGATAAGAGGAGGGGAAAAAGCAGAGTCCACTGTTTAGGAGAGGAG TTGGCCAACGGTGGCGGGTGGGATAGAATAAGGTGGGGGAAAGGGGAGAGGCAAGGTGAC AGGAGGGCTGGGCTGAGGGAGCCAAGGGCTAGACCCTCCCCTAACCCCTGTGTGTCCCCT CCTATTACAGCCCAAAGATCCCTGTGCAGCTCCGATTTTATTCGCATCCTTGTGATCTTC TCTGGAATGTTCCTTGTTTTCACCCTGGCCGGGGCCCTGTTCCTCCATCAACGAAGGAAA TATAGATCAAGTAAGAGACAGAACACAGGCCTCCGGTCCTGCCCCTGCACCACACCCCAC TGGCTCAACCCCACTGCCCACGCCTGGAATCTCACTGAAACCCACCAGCTCCACTTCACC AGCCTTGGTCCTACCCCTTCTCTCCCCTTAGCTGGCGTGCTCCTGACACCCCTCCCCCAA GCGCACCCGCCTCTACCCATCTCCTTCTCCCGTCTCCCCCTGCCCCCACTGCTGGCCAAG ACTCATCGGATCTCCTTCTGCAGACAAAGGAGAAAGTCCTGTGGAGCCTGCAGAGCCTTG TCATTACAGCTGCCCCAGGGAGGAGGAGGGCAGCACCATCCCCATCCAGGAGGATTACCG AAAACCGGAGCCTGCCTGCTCCCCCTGAGCCAGCACCTGCGGGAGCTGCACTACAGCCCT GGCCTCCACCCCCACCCCGCCGACCATCCAAGGGAGAGTGAGACCTGGCAGCCACAACTG CAGTCCCATCCTCTTGTCAGGGCCCTTTCCTGTGTACACGTGACAGAGTGCCTTTTCGAG ACTGGCAGGGACGAGGACAAATATGGATGAGGTGGAGAGTGGGAAGCAGGAGCCCAGCCA GCTGCGCCTGCGCTGCAGGAGGGCGGGGGCTCTGGTTGTAAAACACACTTCCTGCTGCGA AAGACCCACATGCTACAAGACGGGCAAAATAAAGTGACAGATGACCACCCTGCA OMIM ID 186711