Entrez gene ID | | 9414 |
Official gene symbol | | TJP2 |
Full name | | tight junction protein 2 (zona occludens 2) |
Aliases | | ,MGC26306,X104,ZO2, |
Gene summary | | This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutation in this gene have been identified in patients with hypercholanemia. Alternate splicing results in multiple transcript variants. |
Location | | Chromosome: 9 Locus: 9q13-q21 |
Gene position | | 71736224 - 71870124 Map Viewer |
Gene orientation | | plus |
Gene size | | 133901 bp |
Gene sequence |
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OMIM ID | | 607709 |
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