Entrez gene ID | | 94160 |
Official gene symbol | | ABCC12 |
Full name | | ATP-binding cassette, sub-family C (CFTR/MRP), member 12 |
Aliases | | ,MGC27071,MRP9, |
Gene summary | | This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16q12.1 |
Gene position | | 48180681 - 48116884 Map Viewer |
Gene orientation | | minus |
Gene size | | 63798 bp |
Gene sequence |
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OMIM ID | | 607041 |
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