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Gene information for CYP7B1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9420
Official gene symbolCYP7B1
Full namecytochrome P450, family 7, subfamily B, polypeptide 1
Aliases,CBAS3,CP7B,SPG5A,
Gene summaryThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq]
LocationChromosome: 8   Locus: 8q21.3
Gene position65711348 - 65508529  Map Viewer
Gene orientationminus
Gene size202820 bp
Gene sequence
OMIM ID603711