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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ECEL1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 9427 Official gene symbol ECEL1 Full name endothelin converting enzyme-like 1 Aliases ,DINE,ECEX,XCE, Gene summary This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes. [provided by RefSeq] Location Chromosome: 2   Locus: 2q36-q37 Gene position 233352532 - 233344537  Map Viewer Gene orientation minus Gene size 7996 bp Gene sequence >ECEL1:complement(83553955..83561950):Length=7996 GGGCGCTGGGAGACACCGGACGCCCGCTCGGCTGCGCTGCGGCTCAGGCCCCCGCTCGGG CCCGACCCGCTCGGTCACCGCCGGCTCGGGCGCGCACCTGCCGGGTAAGTGGCGCCCGAG TCCCTGCCGCTGAGGCCACCACCGCGGCCACTTCCGTCGCCGCCGCCGCCACTGCGCGGA GCCTCCCGGCTTTGTCTGCGTCCTCTCGGCTGCGGCTCCGGCTGCGGCTGCGGCTGCGGC TCCCGGGCTCGGCTCTCGGGCTCCGCGGACTGCGCCGCACGGCGCCGGGGCTCGGGGGTC GCCAGCCAGCTCGCTCCCCGCCGGGGGTGAAACTTCGCCCAAGTTTGGGTTCTGGGGAGA ACCTGTTGAAGCCAGGAGTGGCTCGGGGCGGGGACAGAGATGGTGGGAGTGGGGGGAGGG AACCCGTCTCGGGTTCTCCATCAGGGCCGTCCAGTGGGTGGGTTGTGTGTCCGCCACCCT GGGGCGTTGGCGCGCGCCCCTAGGGAAGGGGCGAGTGGGCCGTCGGGCCACCGAGCAGAA GGAGCCAGGGAGCGGGGTTGGCGTGGTCGATCCCGCGGACTTCCGCGAGGACAAAGTTTG GTTCTTTGGCCGCTTTGCGGAGCGTCTGTCTGGGTCCAGCGCGGAGAGCTGAAAGTGTCG CATAGACGCGCCCCTGACCGCACCTCCTCACTCCAGCCTCCGCTTCTTCCCCCACTCCAC CCGGCCTTGGCTGGGGCAGGTCGTGGAAGAGAAAGGCGAAGGGGAAGAGGGACGACCTTT CAATGAAGGCCCACTACGTGCCAGGCCCCTTGCCTGGCGCCTCTTGCTTCCAATAAGAGC CCTCCCAACCCTGCGGCCCTCAAGTGTGTGCAGGGAGGGGACAGGGGGGAAGACTCCACT GTGCACCCGGGGGTGGTGGCCCCGCCGAACCCTCATAGTCCCTGGTTTCCGCAGTGAATG AGGCCCGCGGCTGGGGCCTCTGCACCCAGGCCTGTGTCCCTCCTCGCGGTGACCCTGAGC CCCATCCGGCTGCGGCGCCTCCTGAGCCTGCTTCCGCCCTTCCCGCAGCTGCGGCCCCAG GGCCATGCGGAGGCCCACGAGGAGGCCGGCGGCCACGCGCATCCCGTAGCCCAGGTGGCC CAGGTCTGCACCGCGGCGGCCTCGGCGCCATGGAGCCCCCGTATTCGCTGACGGCGCACT ACGATGAGTTCCAAGAGGTCAAGTACGTGAGCCGCTGCGGCGCGGGGGGCGCGCGCGGGG CCTCCCTGCCCCCGGGCTTCCCGTTGGGCGCTGCGCGCAGCGCCACCGGGGCCCGGTCCG GGCTGCCGCGCTGGAACCGGCGCGAGGTGTGCCTGCTGTCGGGGCTGGTGTTCGCCGCCG GCCTCTGCGCCATTCTGGCGGCTATGCTGGCCCTCAAGTACCTGGGCCCGGTCGCGGCCG GCGGCGGCGCCTGTCCCGAGGGCTGCCCTGAGCGCAAGGCCTTCGCGCGCGCCGCTCGCT TCCTGGCCGCCAACCTGGACGCCAGCATCGACCCATGCCAGGACTTCTACTCGTTCGCCT GCGGCGGTTGGCTGCGGCGCCACGCCATCCCCGACGACAAGCTCACCTATGGCACCATCG CGGCCATCGGCGAGCAAAACGAGGAGCGCCTACGGCGCCTGCTGGCGCGGCCCGGGGGTG GGCCTGGCGGCGCGGCCCAGCGCAAGGTGCGCGCCTTCTTCCGCTCGTGCCTCGACATGC GCGAGATCGAGCGACTGGGCCCGCGACCCATGCTAGAGGTCATCGAGGACTGCGGGGGCT GGGACCTGGGCGGCGCGGAGGAGCGTCCGGGGGTCGCGGCGCGATGGGACCTCAACCGGC TGCTGTACAAGGCGCAGGGCGTGTACAGCGCCGCCGCGCTCTTCTCGCTCACGGTCAGCC TGGACGACAGGAACTCCTCGCGCTACGTCATCCGCGTGAGTGCGCCCCCTGAGCGCCCTG CCAGCGGCCGCGGATCCGGGGCGCAGTGGCCTTGCCCAGGGGTCCCTGCGCGCGGGAGGC GGGTGCGTGAGAGGAGAGGAGGGAAGAGACGAGCAGGAGAGGGGAGGGGAGGGGAGCGCA CAGAGGCAGAGCGCGGGAGGAGGGCGCAAGTAATTTCCCTGGGGTAATTGCGGTGTTTAG AGGAGCCGCGGGAGCCGCAATTTCCCAGCCCTCTGGCAGGCAGTGAGGGCCAGGAGGGAG AGGCGCGCCGGCGGGCTGGGTTGACGTCTCCGCGAGGTCTGGAGCTGGCCCCAAAGCTAG GGGTCCCAACTGTCAGTGGGGGACCTACGAATGCCCCGGACAGATAAGGAAAGTGCAGAC GTACAGGGGTAAGATTGGGCATCCGCAGGCTGGGACAGTCAGGGATGGGGCTTTGGCCAT CTCGTCTGGGTGGAAAGAGGAGCTGGGGTCTGCGTGCTTCTGTGGCTGTACTCATGGATG TCTGGTTGCTCTCTGGGCATTGGAGTGGGAATTCCCTCTGTTTAGGGAACCTGAGGTGTG GGCCTCTGACCTGTGGCCCCTGTCTCCCTCCCCAGATTGACCAGGATGGGCTCACCCTGC CAGAGAGGACCCTGTACCTCGCTCAGGATGAGGACAGTGAGAAGGTGCTGGGGCATGGGA TGGGGAGGCAGGGAAGGCCTGGGGCCCCAGGAGGGGTGGATCCAGGCTAGGCCTGTCCCT GTCCCTGGGTGAGCCCCCTCCCCTGGTGCAGATCCTGGCAGCATACAGGGTGTTCATGGA GCGAGTGCTCAGCCTCCTGGGTGCAGACGCTGTGGAACAGAAGGCCCAAGAGATCCTGCA AGTGGAGCAGCAGCTGGCCAACGTGAGCAGACCAGGACTGGAGGCTGCCCTGGGCTTGAG GGAGGGCATCATGGAGCAGGGCTGGGTCAGCTGTGATCTCTCCCCACAGATCACTGTGTC AGAGCATGACGACCTACGGCGAGATGTCAGCTCCATGTACAACAAGGTGACGCTGGGGCA GCTGCAGAAGATCACCCCCCACGTGAGTGTGGCCCAGTCCTCGTGGGCAGGCAGGGTTGA GGGCAATGCTGCTGCTGGGACTACAGGGTCATCTCTCCCCAGAGATGGGCAAACCGTTCC TTGGCCATGGACTCTCATGTCCCCTCGCTGCCTCTCTCTGCCCCCTCCCTGTCTTCTGTG GCCCCTGCCAACCCTAGCCTCACTGTCCCTGTCCTTGGTCTCACAGTTGCGGTGGAAGTG GCTGCTAGACCAGATCTTCCAGGAGGACTTCTCAGAGGAAGAGGAGGTGGTGCTGCTGGC GACAGACTACATGCAGCAGGTGTCGCAGCTCATCCGCTCCACACCCCACCGGTATGGCTG CAGATCTGGCATTTTCTGCCCAGCGGTCACTAGGTCCTTCCCCTGCACCCTGGACCTCTC TGCTGGGTGGGCTTTACATTTTCTGCTCTGCATAGCTGGGATGACCCCCTGTCCCTTCTT TGTGGGGCTGTCTGGGTCCTGGGTCCAGCCACAGGTTGGCGGGCACAGGTAGGGGTGGTG CCCTTGGTGGCCCACATGCATGTCCGTCTGGACACCCACTGGCTTCACCTGGTCCCCAGG GTCCTGCACAACTACCTGGTGTGGCGCGTGGTGGTGGTCCTGAGTGAACACCTGTCCCCG CCATTCCGTGAGGCACTGCACGAGCTGGCACAGGAGATGGAGGGCAGCGACAAGCCACAG GAGCTGGCCCGGGTCTGCTTGGGCCAGGCCAATCGCCACTTTGGCATGGCGCTTGGCGCC CTCTTTGTACATGAGCACTTCTCAGCTGCCAGCAAAGCCAAGGTGGGTTGCCCTTGTTTG AGAGAGGAGGATGGTGCTGAACTGAGGGTGGAGCCCTCCCGAGGCCATGGTCCTAATATG GGGAGCCCCACATGTCCCCTGCAGGCAGGGGGACCAGGCCCTGCTAAGTACTCAGCCGAT TCTGAGGCCCCAGGCTGCTCCTCCACAGGCCTCCTCCTCCAGGAAGCTTATGTGGACTAT CAACTGCAGGCAGACCTCCCTGCCAGGCCCCAGCCCACCTTCTCAGGCATGCTCGGGAGG CGTGGCCTTAGGGATGTCTGTGGTCATTGCTGGGGCAGTTTCCTCCTCTATCTTGTGAGC CCTCGGGGGTGCAGGGCCTGGATCCTCACCTCCAAAGTATCCTCTTGGTGTTCAGAAATG AGGTTTGGGCTTAGAAAGTGGTGCTTAAAGGCAGGGGTACCCCTCCTGCCAGGAGTGATA GACCAGGCTGCTGGGTTGACCCTTGCTCCCTGACCCCTGACCCTGCAGGTGCAGCAGCTA GTGGAAGACATCAAGTACATCCTGGGCCAGCGCCTGGAGGAGCTGGACTGGATGGACGCC GAGACCAGGGCTGCTGCTCGGGCCAAGGTGAGGGGGGACCCAGTGTCATTGGTTGGTCCC ATATATATTGAGCACCTACTGTGTACCAGCGAAAGAGAACAAAAGGGACAAAGAGGCCTT CGTGGAGTTGACCAGGCCTGCCTCCCCCACTGTGAAGCCCACTCCCAGGCTGGCCTAGTG CTCCCTTCCTTGGTGGGTAGGGTGGGGGGCGGGGGGCTGTCTCCCGAGGCCTGGTGCCAC CTTCACCTGCCCTCGGCCCGCAGCTCCAGTACATGATGGTGATGGTCGGCTACCCGGACT TCCTGCTGAAACCCGATGCTGTGGACAAGGAGTATGAGGTGGGCCCTGACCCTGCCTGCC CAGCCTGTCCACAGCCCCTCTACTAACGGCACTCAGGAGGGCAGGTGGCCTGCACGGCCA GGTTGTTGCCCAGTCTGCAGGTAGCCCTGCCCTGGCCTGCCGCTGAGTGTCGCCCGTGCC TCCTGCAGTTTGAGGTCCATGAGAAGACCTACTTCAAGAACATCTTGAACAGCATCCGCT TCAGCATCCAGCTCTCAGTTAAGAAGATTCGGCAGGAGGTGGACAAGTCCACGTGGGTGC CTGGCCCAGAGCTGGGGGTCAGGGAAGGGTTGTGGGGAAAGGGCAGGAGCTGGTAGGGCA AATCGTCTCACAGCCATGCAGATATGGGGGGCACACACGCCAGCACAGGGCATGGGGTGG GGGCCGGCAGGGTGACCCCCAGACTGTCAGGAGATGGCTGACGAGGAAGCTGTGATGTGA GGGTAGCGGGGGAGGGAGTGTGTTCCCCCCATTCACCCCAGCATCCCTCCACAGGTGGCT GCTCCCCCCACAGGCGCTCAATGCCTACTATCTACCCAACAAGAACCAGATGGGTAAGGG GATGTGTCCCTACGCCGGGCGGGGCAGGGTCCGAAAGTGGATGGGTTTCCCACTGAGCAC CCCCTTCTTGTAGTGTTCCCCGCGGGCATCCTGCAGCCCACCCTGTACGACCCTGACTTC CCACAGTGAGTACATAGCTTGCCCTGTTTGTGGCTGAGGGCAGGGCTGGCATTGCAGACC TTGTCTACCAGGTGTGTGTCGGCGTACTGTGGCTCCAATCGCCCCAGACCCAGCTGGGTT CAGGAGTCAGGACAGCTGTGGACCCTGGCTCCCCACTACATCCTTGGTTATTTAGAAAAA TGTGTAGGTTTGTTATTTGTAACTTCCTGGGGTCTTCTTTACTTGTTTGAGGCTCATTTT GATGTTTCAAAGGTGGCGCAACACTAATGATGAGGTAGGAGGAGAAACCCCTACGTAGGT GCCTCCGTTTCCCTCCTGTCTCCTCCAGCCCTGTTTCACTGCCCAGCCAGCTCTGTTAGA TGTGATTTCCTAAAAGAAGCTGGATAGGTTCCACTGGCATTCACATAGCGCATGAGGAAG CTGAGGCACATGTGCCCCTGGACCGCACGGATGCCTCTGTGGCCTCCCTGTGCCACCTCC TGGCCCGGCCAGGGGACATCTGGGGCCTGGGCAGCAGCATGGGGCTCTCAGAGGGTGGAG GGCTAGGGCCTGATGCTGCTGCTGTGGGCCCAGGTCTCTCAACTACGGGGGCATCGGCAC CATCATTGGACATGAGCTGACCCACGGCTACGACGACTGGGGTGAGGCCTGTTGGGGCCC CAGGGGATGGCCCGGAGGGGGCAGGACAGGCAGTGGAGAGGCAGGGTAGGGGATGGCCTA ACTGGGGCTGGTGGGTGGGGAGGGGAGGGGGCTCAGGTGAGGGTGGGTCTCAGCCTGCTG CACTGCCCACAGGGGGCCAGTATGACCGCTCAGGGAACCTGCTGCACTGGTGGACGGAGG CCTCCTACAGCCGCTTCCTGCGAAAGGCTGAGTGCATCGTCCGTCTCTATGACAACTTCA CTGTCTACAACCAGCGGGTGAGACCCCCACCTGCCCCTTGTGCCCCTCAGGCCTGGTGGG GCACGGGCCGGGAGCATCACGCACACCCTTGCGCACGTGCACATGTCCAAACAAAACCTG TGCCCAGGTCCCTGCACACACATTCGGTTCCCACGCACACTCACGTGGACAGATAATGAG TGTCCGCAGACTTACGGAGGACAAGGGGGTTGGGAGGAAAGAGTAGGGTTGGAGCCCCCC CTCAAACTCTCTGGGCAAGGGAAGGAGAGGGGTGGTAGGAATTAGGGGCTGGGGCCCAGG GTATCAATGCCTGAGGGAGGCCAGCTGGGCCCCAAGCAGCCCCCTGGCCTCTTCCCTTCC CGGCAGGTGAACGGGAAACACACGCTTGGGGAGAACATCGCAGATATGGGCGGCCTCAAG CTGGCCTACCACGTGAGCGGCCTGCCTGTGCTCCACCCCTGCTGCAGGAGGGACGGGGGC TGATGAGGACTCCAGATGAGGGACAGAGCTGCCTCTCCCTGCCCACCCTGCTGAGCTCTG GCCTGGGGTGGGGCAGGGCATGTGCTGGGGCCACGGTCCACTGGAAGAGGAAGGATTCAC GGGCCCCCCTTCACAGGGAGAGCAGGGAGGGCTACCTAGATGGAGGACAGAGAAGAAGCG GTGCCCAGGGTGGGCGGGCATAGCAGGTCCATGCTCTCTGTGTCCCCAGGCCTATCAGAA GTGGGTGCGGGAGCACGGCCCAGAGCACCCACTTCCCCGGCTCAAGTACACACATGACCA GCTCTTCTTCATTGCCTTTGCCCAGGTGGGCTGGGTGGGGGATTGGACTGGGAGCCTTGG GGTGGGGACACGGCATCCAGGGTCAGTCCCAGTCCTGCCTTGCCCAGGCTTCGCATGGAC AGCCTGTCTGTCATCACCTGTCCCGTCAGAGGTGATGGTCCTGTGGTGCTGAGGGGGCCT ACCGCCTTGTGTGCTGGGTGGGGGGCAAGGGGGCGGATGCCTGGCTTCATCTCCCCCTCC TCCCCTCCACCCCGCTCCTGGACCCAGAACTGGTGCATCAAGCGGCGGTCGCAGTCCATC TACCTGCAGGTGCTGACTGACAAGCATGCCCCTGAGCACTACAGGTATGCCCACCTGCCC GCCTGGCCTTGTCCACTCCTTGTGTTTGGGGTGGGATCAGGGGGCATGGGAAGGAATAAA AGTCACCCCTGGTTGCTGGGGCTGGAGTGGCTGCAGGGCCCAACACTGTGTGGGTCTCTC CCCACCCCAGGGTGCTGGGCAGTGTGTCCCAGTTTGAGGAGTTTGGCCGGGCTTTCCACT GTCCCAAGGACTCACCCATGAACCCTGCCCACAAGTGTTCCGTGTGGTGAGCCTGGCTGC CCGCCTGCACGCCCCCACTGCCCCCGCACGAATCACCTCCTGCTGGCTACCGGGGCAGGC ATGCACCCGGTGCCAGCCCCGCTCTGGGCACCACCTGCCTTCCAGCCCCTCCAGGACCCG GTCCCCCTGCTGCCCCTCACTTCAGGAGGGGCCTGGAGCAGGGTGAGGCTGGACTTTGGG GGGCTGTGAGGGAAATATACTGGGGTCCCCAGATTCTGCTCTAAGGGGGCCAGACCCTCT GCCAGGCTGGATTGTACGGGCCCCACCTTCGCTGTGTTCTTGCTGCAAAGTCTGGTCAAT AAATCACTGCACTGTT OMIM ID 605896