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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ABCG2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9429
Official gene symbolABCG2
Full nameATP-binding cassette, sub-family G (WHITE), member 2
Aliases,ABC15,ABCP,BCRP,BCRP1,BMDP,CD338,CDw338,EST157481,MGC102821,MRX,MXR,MXR1,
Gene summaryThe membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q22
Gene position89080011 - 89011416  Map Viewer
Gene orientationminus
Gene size68596 bp
Gene sequence
OMIM ID603756