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Gene information for AKAP5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9495
Official gene symbolAKAP5
Full nameA kinase (PRKA) anchor protein 5
Aliases,AKAP75,AKAP79,H21,
Gene summaryThe A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q21-q24
Gene position64932217 - 64941221  Map Viewer
Gene orientationplus
Gene size9005 bp
Gene sequence
OMIM ID604688