Entrez gene ID | | 9508 |
Official gene symbol | | ADAMTS3 |
Full name | | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
Aliases | | ,ADAMTS-4,KIAA0366, |
Gene summary | | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q13.3 |
Gene position | | 73434516 - 73146687 Map Viewer |
Gene orientation | | minus |
Gene size | | 287830 bp |
Gene sequence |
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OMIM ID | | 605011 |
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