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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ADAMTS1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 9510 Official gene symbol ADAMTS1 Full name ADAM metallopeptidase with thrombospondin type 1 motif, 1 Aliases ,C3-C5,KIAA1346,METH1, Gene summary This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq] Location Chromosome: 21   Locus: 21q21.2 Gene position 28217728 - 28208606  Map Viewer Gene orientation minus Gene size 9123 bp Gene sequence >ADAMTS1:complement(13870477..13879599):Length=9123 GCACTCGCTGGAAAGCGGCTCCGAGCCAGGGGCTATTGCAAAGCCAGGGTGCGCTACCGG ACGGAGAGGGGAGAGCCCTGAGCAGAGTGAGCAACATCGCAGCCAAGGCGGAGGCCGAAG AGGGGCGCCAGGCACCAATCTCCGCGTTGCCTCAGCCCCGGAGGCGCCCCAGAGCGCTTC TTGTCCCAGCAGAGCCACTCTGCCTGCGCCTGCCTCTCAGTGTCTCCAACTTTGCGCTGG AAGAAAAACTTCCCGCGCGCCGGCAGAACTGCAGCGCCTCCTTTTAGTGACTCCGGGAGC TTCGGCTGTAGCCGGCTCTGCGCGCCCTTCCAACGAATAATAGAAATTGTTAATTTTAAC AATCCAGAGCAGGCCAACGAGGCTTTGCTCTCCCGACCCGAACTAAAGGTCCCTCGCTCC GTGCGCTGCTACGAGCGGTGTCTCCTGGGGCTCCAATGCAGCGAGCTGTGCCCGAGGGGT TCGGAAGGCGCAAGCTGGGCAGCGACATGGGGAACGCGGAGCGGGCTCCGGGGTCTCGGA GCTTTGGGCCAGTACCCACGCTGCTGCTGCTCGCCGCGGCGCTACTGGCCGTGTCGGACG CACTCGGGCGCCCCTCCGAGGAGGACGAGGAGCTAGTGGTGCCGGAGCTGGAGCGCGCCC CGGGACACGGGACCACGCGCCTCCGCCTGCACGCCTTTGACCAGCAGCTGGATCTGGAGC TGCGGCCCGACAGCAGCTTTTTGGCGCCCGGCTTCACGCTCCAGAACGTGGGGCGCAAAT CCGGGTCCGAGACGCCGCTTCCGGAAACCGACCTGGCGCACTGCTTCTACTCCGGCACCG TGAATGGCGATCCCAGCTCGGCTGCCGCCCTCAGCCTCTGCGAGGGCGTGCGCGGCGCCT TCTACCTGCTGGGGGAGGCGTATTTCATCCAGCCGCTGCCCGCCGCCAGCGAGCGCCTCG CCACCGCCGCCCCAGGGGAGAAGCCGCCGGCACCACTACAGTTCCACCTCCTGCGGCGGA ATCGGCAGGGCGACGTCGGCGGCACGTGCGGGGTCGTGGACGACGAGCCCCGGCCGACTG GGAAAGCGGAGACCGAAGACGAGGACGAAGGGACTGAGGGCGAGGACGAAGGGGCTCAGT GGTCGCCGCAGGACCCGGCACTGCAAGGCGTAGGACAGCCCACAGGTAGAAGAATTGCTC TCGTTTGTCTGTCCATTCATCCTCCTCTCCTCACTTTATCTATCCCACGCGACTTCAGGG TAGACTCCTGCTGGCAGGCAGGATCATAAGTCCGCGGACAGAACGGAGGCCTGGAGTGGA GGAATGTGGTTTGAGGTTTGGATTGGTGAACTCAGCTAGAAAACATACTTGCATTTGCCC GAATAATGAATAACCAAGAAAAAAACTGACAAACGATTTTCTGCAAACTAAAGCAAAGCA TTTAGGCCGGGGAGGGAGAGTTTGTAACCTGACTCCTTCCACCTTTAGCGAGTTGGAGCT TGTGCGAGTTCTTTCCACTCTGTGTATTTCTTTTTAATGATTTTGTGTGCGCCTTTTGTG CGGGTTGCAACGTTGCGCTGAGTTTTGTAACCGCTGCCTGTGCGTGCATCCTGCGCTCAC GGGAGGGCGGATGTGGAGAGGGCAGAGGAGCAATGGTGACCTGGGAAGGTACCCTGAGCG GCTACGCTAGGATCTCTGTTCTGCAGACTTCTGTCCCCTTTCCCCCTTATAAGGCTGACC CAGGCGGGCTGAAGGCGGTGGGGCCCCTTCGCAGAACCTGCTTGGGAGGTCTTTCCCGGG TTTGCCCCGCCTCCCAGTTTGCACTCCCTCTCGCGGCCATAATTCTGCTCTCAAGCACTG TTGAAAGTCACTGCCGGTCCTTCCTGCTACGGCCTTCTCTCTGTGCAGTGCTTATTCTCC AGTTCTTTTTGTTTCATCACTTTGGTGCCTTTTTCCTTCTTTAACTCTCTCGCGTGTCAT TTTTTAAAGAATTCTCCCCTTTTCCCCTGCTCCTCTGCTCCTGGGAGCAAAGTGGTCGCA GCCCAGTTTAGGACTTTCTGCAGGGGTTGGGTCTCAGTCCGGAGTGGAAGGCTCTGTTCC AAATAATCAATCATGCCTGGAAGCTGGAACTTATTTCGCTGGGGCAGTGGGAGTGGGGCC AGAGGCTGCTGGGCAGAGTGGGTGGTCCTTGTGCCCGGAATTGGCAAGAGCGGAGCACCC CAGGGACCCCTGGAATGAGACAGCAGAGCTGTGCAGTCTGAGATTCCTTAAGGCCCGGCC CCTTGGCAGCAGCCCAGGCCCTACCCGAGGCCTTCCACGTGGAGCCTGATGATCTCATTC AGGATTTGAGCCCTCGCCTGTGAAAGAGTGACTCAGGGCCTCTGCCTGCCGCTCTTGCTC CAAGATTTTACTACAATTGGGTAGGATTATGTGCGAAATTGCCTTGTTCAGACTGTGGGA TTTCAAAGAGAACAGAAGAAATCCTGCTCACACACAGAAAGATCCTGACCATGCAAAGGA GCGCGTGGTCTTTTTATTTAAAGGAGAGGAGAGAACTTTAAAAATAACACTTGGAGTGAA GATATGCAAATATTTTTGTTATTGTTGTTCTGGGTATATTTTTGCTTTGTTTGCTTTGAC TGGTTAGGCTTTCCTAATATATGCTAGGAAGGTAACTATTCTTGGACAGCCTGACCATAA GCAAACTTTTTTTTTTCTTTACAGGAACTGGAAGCATAAGAAAGAAGCGATTTGTGTCCA GTCACCGCTATGTGGAAACCATGCTTGTGGCAGACCAGTCGATGGCAGAATTCCACGGCA GTGGTCTAAAGCATTACCTTCTCACGTTGTTTTCGGTGGCAGCCAGATTGTACAAACACC CCAGCATTCGTAATTCAGTTAGCCTGGTGGTGGTGAAGATCTTGGTCATCCACGATGAAC AGAAGGGGCCGGAAGTGACCTCCAATGCTGCCCTCACTCTGCGGAACTTTTGCAACTGGC AGAAGCAGCACAACCCACCCAGTGACCGGGATGCAGAGCACTATGACACAGCAATTCTTT TCACCAGACAGGTAAGAGGAAGATGGTACCAGCTGTGAGACTGTCCTCTTAGGAGTCTAC GTTGTACCAAAAAGATATATACAAGGCATTTCACCAGTGTTTTTGCAGTTAACCTTTTTT AATTGGCTAGCATGGTTTATCTTACTCATTTCTACTGTAATTTAAATATCTCAAGTTTCA CAGTTCTATTTTAAAAGCATTAGAAAAAAGCTTGATTAAAGTCACATGAAGTCTTCTTAT GTCAACAATAATGAATGTAGATGCTCCAAAGCATATGTGAAGGCACACCCTGCCAAAAAA GTTAGATCCCAAGGGTCATGCTCCCCTTATTAATAAGTATTTACCTTTGCTTTTTGTAGG ACTTGTGTGGGTCCCAGACATGTGATACTCTTGGGATGGCTGATGTTGGAACTGTGTGTG ATCCGAGCAGAAGCTGCTCCGTCATAGAAGATGATGGTTTACAAGCTGCCTTCACCACAG CCCATGAATTAGGTAAGTCTGCTTCAAAGTAGAAGTTAAGCTCAATTCAGAAATGTAAAC TGGTAAAACAATATAAGAAGGAGAGTCTGTAGGTTATATTGCTATTTTAGGTCCTAGTGC ATCTTAGAAACTATAGAAAATATTTTGTCACTATTTCAAACATGGTCATTTTTATTAAAG TAAAAAATAAGATAGTAGTAGCTCTGGACATTTGGAAATGTGTATGTTTGTTTACACCCT GTGAAAAGTAGACATGGTCTGCAAAAGAGCCAATCTCCTAAATATATTTCTTTCTCTAGA AATGTTATTTTGGGACAAATGAATGAATCCCTGTTGGGAAAAAAGAACCTGCTGCATATC ATCCATATTTTATTTTATTATTATTTTTTTTGAGATGGAGTCTCACTCTGTCTCCCAGGC TGGAGTGGAGTGGCACAATCTCGGCTCACTGCAACTTCTGCCTCCTGGGTTCAAGCGATT CTGCTGCCTCAGCATGCCCAGTAGCTGGGATTACAGGTGCATGCCACCACACCCGGCTAA TTTTTGTATTTTTAGTAGAGACGGGGTTTCACTATGTTGGCCATGCTGGTCTTGAACTCC TGACCTCAAGTGATCCACCCGCCTCGGCTTCTGGAATTACAGGTGTGAGCCACCGCACCC AGCCATGATCCATACTTTAATGTGGGTTCTGGATTGCTTCCTAGGCCACGTGTTTAACAT GCCACATGATGATGCAAAGCAGTGTGCCAGCCTTAATGGTGTGAACCAGGATTCCCACAT GATGGCGTCAATGCTTTCCAACCTGGACCACAGCCAGCCTTGGTCTCCTTGCAGTGCCTA CATGATTACATCATTTCTGGATAATGGTCATGGTGAGATATTCCAGCTACTCTCTCTAGA TGGCATCCAACCTTTCACGCATAAAGTTTAGTTAAATGAACTCTTTCCTTTTTGTTCTTT TTATTTTCCCCACTTCAAAATTACTTTTCCTCTGTCAAGATCCTAACTGTTGAGATCTTA ATTCCAAATAAAAAATAGTGCTTCCGGTTGAGTAGCTCCCAAAGCCCATTCATTCACATT GTTCGCAGATCAATAACTTCCTGTCATTGTTAATATAGAAATACCCCATTGAGGATAAGA TCTTAATAGTAATCTAAATCTCTTCAGCATTTCCCTCCCCCAGCTTTACAGTTTTCAGAT CACTTTGCTGTCTATTTTCTCATATGATAAATATTTTCTGAAATGGGATCTACCCCTTCA TGCCCTCACTAACTCTGTATTGATATTGGTTGGCATTTCCTTTGCAGGGGAATGTTTGAT GGACAAGCCTCAGAATCCCATACAGCTCCCAGGCGATCTCCCTGGCACCTCGTACGATGC CAACCGGCAGTGCCAGTTTACATTTGGGGAGGACTCCAAACACTGCCCCGATGCAGCCAG CACATGTAGCACCTTGTGGTGTACCGGCACCTCTGGTGGGGTGCTGGTGTGTCAAACCAA ACACTTCCCGTGGGCGGATGGCACCAGCTGTGGAGAAGGGAAATGGTGTATCAACGGCAA GTGTGTGAACAAAACCGACAGAAAGCATTTTGATGTGAGTTTTTCTACTGAAACACATTC AGAATTGAAAAGAACAAAGTGATGGTAAAAGATATGATACCAAGTTAAACATCCCCATCC GTGTCCTCTAGCAGGAATGCGAGATAGCTTATTTTTAGAACTGATTCTTTGTCCCATGTG GCTTTCTTTGATACCCTAAAAGTTCTCTTTAGATAATTCTAATGCTGATGATTTATGTCT CCATTTAGACGCCTTTTCATGGAAGCTGGGGAATGTGGGGGCCTTGGGGAGACTGTTCGA GAACGTGCGGTGGAGGAGTCCAGTACACGATGAGGGAATGTGACAACCCAGTCCCAAAGA ATGGAGGGAAGTACTGTGAAGGCAAACGAGTGCGCTACAGATCCTGTAACCTTGAGGACT GTCCAGACAATAATGGTGAGGAGCAACGGACTCTGGTTTTAAGAAACTGGATTAAAAAAA GATGTACCCACAAACAGGTGGCTCAAGATTGGAAACTGATAATGTTATCATATTATTCTC TTTCCAGGAAAAACCTTTAGAGAGGAACAATGTGAAGCACACAACGAGTTTTCAAAAGCT TCCTTTGGGAGTGGGCCTGCGGTGGAATGGATTCCCAAGTACGCTGGCGTCTCACCAAAG GACAGGTGCAAGCTCATCTGCCAAGCCAAAGGCATTGGCTACTTCTTCGTTTTGCAGCCC AAGGTAGTTCGTTTTTACCTTATTTTTACCTAAAAATCAAGGCCTGGGCTTGCTACCTTT TCAAACAATTTTTGTTATACTTTCTTTGCTTTCCATATTAACATATCTTCAATTTCAAAT TTGAACTCCTTTTCTTTTACATTAATTGGCAACTGCCTGCTTTGAGTTTAGTGTTTTCAG TTATGAATGAAGCTTAAATCTAACACTTCACATGCTTGCAATTGCTCGCTATTACTCTTT TATATGCAAAGAAAAGCTTTTTGGACAGTCAAGCGCTCCTCTGTGCGACTAGGCTTCACA TACAGCTCATAGTTAGATACATTTTATATTCACACAGTAACCAGTAGTTTTGGAAAATAG TCTATGCATGGTCCAAAATACTTGTTACTGGGTAACTAGCAGTAGCAGGTGCAAACAGAA TAATAGAAGTGGTAGTCTGAGTATTGATTATTTTTATGTTTGAAAACACATATTGAACTA GGAAAAGCATCATTTCTTTTGCTGTTTTGCTAAGGGAATACATCTGGATCTGAGACAGAA AATGGAATTTAATGTGATTGAGATGATCGTGTGTCATTAGCACCATAGGCTATGAAAATA TTCCCAAGTTGCAGATTCAATATTCAGCAAGTGATTTCTGAAGCACTTACTCTTGCCAGA TACTAATTATTCTAGGCTCTGAAGATACAGCAGTAAACAAAGTGACAAACAGCTCTACTT TCATTGACCTTAGCTGGAGGAGACATAGGTCAATAGATAAATAATTTTTAAAAATATCTA ATTTCTTCAGATGTCTATACGTAGTACTGAAAAATATGCCAAAGTGAAGGGTAAATGCAT GAAATGCATAATGTGTAGAGGGTACTGTGTTTAATTAGCATGGTCAGGAAAGTAGAGAGA AAATGTTTACACTTATCATTGCAGCATCTCCTTCCTTTGCTTGTATGTAACACTAGACAT GTGTCCTTTTTTCAGGTTGTAGATGGTACTCCATGTAGCCCAGATTCCACCTCTGTCTGT GTGCAAGGACAGTGTGTAAAAGCTGGTTGTGATCGCATCATAGACTCCAAAAAGAAGTTT GATAAATGTGGTGTTTGCGGGGGAAATGGATCTACTTGTAAAAAAATATCAGGATCAGTT ACTAGTGCAAAGTAAGTTTTAAAACACCTATTTGCAGACCTTATAATTTAAATGGGCCTT TCAACAGGTCTGGGAAAAAAATATGTCTCATAAAAGATTAATGTGTTTTTAAGCTAAATA ATCTAATTAGCCAATGAATCAGAGATTTATGCCTGTTTTTGTCACCTGCAGACCTGGATA TCATGATATCATCACAATTCCAACTGGAGCCACCAACATCGAAGTGAAACAGCGGAACCA GAGGGGATCCAGGAACAATGGCAGCTTTCTTGCCATCAAAGCTGCTGATGGCACATATAT TCTTAATGGTGACTACACTTTGTCCACCTTAGAGCAAGACATTATGTACAAAGGTGTTGT CTTGAGGTACAGCGGCTCCTCTGCGGCATTGGAAAGAATTCGCAGCTTTAGCCCTCTCAA AGAGCCCTTGACCATCCAGGTTCTTACTGTGGGCAATGCCCTTCGACCTAAAATTAAATA CACCTACTTCGTAAAGAAGAAGAAGGAATCTTTCAATGCTATCCCCACTTTTTCAGCATG GGTCATTGAAGAGTGGGGCGAATGTTCTAAGTCATGTGAATTGGGTTGGCAGAGAAGACT GGTAGAATGCCGAGACATTAATGGACAGCCTGCTTCCGAGTGTGCAAAGGAAGTGAAGCC AGCCAGCACCAGACCTTGTGCAGACCATCCCTGCCCCCAGTGGCAGCTGGGGGAGTGGTC ATCATGTTCTAAGACCTGTGGGAAGGGTTACAAAAAAAGAAGCTTGAAGTGTCTGTCCCA TGATGGAGGGGTGTTATCTCATGAGAGCTGTGATCCTTTAAAGAAACCTAAACATTTCAT AGACTTTTGCACAATGGCAGAATGCAGTTAAGTGGTTTAAGTGGTGTTAGCTTTGAGGGC AAGGCAAAGTGAGGAAGGGCTGGTGCAGGGAAAGCAAGAAGGCTGGAGGGATCCAGCGTA TCTTGCCAGTAACCAGTGAGGTGTATCAGTAAGGTGGGATTATGGGGGTAGATAGAAAAG GAGTTGAATCATCAGAGTAAACTGCCAGTTGCAAATTTGATAGGATAGTTAGTGAGGATT ATTAACCTCTGAGCAGTGATATAGCATAATAAAGCCCCGGGCATTATTATTATTATTTCT TTTGTTACATCTATTACAAGTTTAGAAAAAACAAAGCAATTGTCAAAAAAAGTTAGAACT ATTACAACCCCTGTTTCCTGGTACTTATCAAATACTTAGTATCATGGGGGTTGGGAAATG AAAAGTAGGAGAAAAGTGAGATTTTACTAAGACCTGTTTTACTTTACCTCACTAACAATG GGGGGAGAAAGGAGTACAAATAGGATCTTTGACCAGCACTGTTTATGGCTGCTATGGTTT CAGAGAATGTTTATACATTATTTCTACCGAGAATTAAAACTTCAGATTGTTCAACATGAG AGAAAGGCTCAGCAACGTGAAATAACGCAAATGGCTTCCTCTTTCCTTTTTTGGACCATC TCAGTCTTTATTTGTGTAATTCATTTTGAGGAAAAAACAACTCCATGTATTTATTCAAGT GCATTAAAGTCTACAATGGAAAAAAAGCAGTGAAGCATTAGATGCTGGTAAAAGCTAGAG GAGACACAATGAGCTTAGTACCTCCAACTTCCTTTCTTTCCTACCATGTAACCCTGCTTT GGGAATATGGATGTAAAGAAGTAACTTGTGTCTCATGAAAATCAGTACAATCACACAAGG AGGATGAAACGCCGGAACAAAAATGAGGTGTGTAGAACAGGGTCCCACAGGTTTGGGGAC ATTGAGATCACTTGTCTTGTGGTGGGGAGGCTGCTGAGGGGTAGCAGGTCCATCTCCAGC AGCTGGTCCAACAGTCGTATCCTGGTGAATGTCTGTTCAGCTCTTCTGTGAGAATATGAT TTTTTCCATATGTATATAGTAAAATATGTTACTATAAATTACATGTACTTTATAAGTATT GGTTTGGGTGTTCCTTCCAAGAAGGACTATAGTTAGTAATAAATGCCTATAATAACATAT TTATTTTTATACATTTATTTCTAATGAAAAAAACTTTTAAATTATATCGCTTTTGTGGAA GTGCATATAAAATAGAGTATTTATACAATATATGTTACTAGAAATAAAAGAACACTTTTG GAA OMIM ID 605174