Entrez gene ID | | 9538 |
Official gene symbol | | EI24 |
Full name | | etoposide induced 2.4 mRNA |
Aliases | | ,PIG8,TP53I8, |
Gene summary | | This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q24 |
Gene position | | 125439298 - 125454575 Map Viewer |
Gene orientation | | plus |
Gene size | | 15278 bp |
Gene sequence |
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OMIM ID | | 605170 |
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