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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for EI24 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9538
Official gene symbolEI24
Full nameetoposide induced 2.4 mRNA
Aliases,PIG8,TP53I8,
Gene summaryThis gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q24
Gene position125439298 - 125454575  Map Viewer
Gene orientationplus
Gene size15278 bp
Gene sequence
OMIM ID605170