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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NRG2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9542
Official gene symbolNRG2
Full nameneuregulin 2
Aliases,Don-1,HRG2,NTAK,
Gene summaryThis gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q23-q33
Gene position139422884 - 139226364  Map Viewer
Gene orientationminus
Gene size196521 bp
Gene sequence
OMIM ID603818