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Gene information for MRPL33 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9553
Official gene symbolMRPL33
Full namemitochondrial ribosomal protein L33
Aliases,C2orf1,L33mt,MGC111093,MGC13694,MGC23922,MRP-L33,RPL33L,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p21
Gene position27994584 - 28002608  Map Viewer
Gene orientationplus
Gene size8025 bp
Gene sequence
OMIM ID610059