Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CD44 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID960
Official gene symbolCD44
Full nameCD44 molecule (Indian blood group)
Aliases,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MGC10468,MIC4,Pgp1,
Gene summaryThe protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq]
LocationChromosome: 11   Locus: 11p13
Gene position35160417 - 35253949  Map Viewer
Gene orientationplus
Gene size93533 bp
Gene sequence
OMIM ID107269