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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RNF7 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9616
Official gene symbolRNF7
Full namering finger protein 7
Aliases,CKBBP1,ROC2,SAG,
Gene summaryThe protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q22-q24
Gene position141457051 - 141465243  Map Viewer
Gene orientationplus
Gene size8193 bp
Gene sequence
OMIM ID603863