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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TRAF4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 9618 Official gene symbol TRAF4 Full name TNF receptor-associated factor 4 Aliases ,CART1,MLN62,RNF83, Gene summary This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq] Location Chromosome: 17   Locus: 17q11-q12 Gene position 27071023 - 27077976  Map Viewer Gene orientation plus Gene size 6954 bp Gene sequence >TRAF4:1808017..1814970:Length=6954 ACCGCCAGTCGGCGCCGCCCGGAGCCGGGAGCGCCGCTCCAGCGAGGCGCGGGCTGTGGG GCCGCCGCGTGCCTGGCCCCGCTCGCCCGTGCCGGCCGCTCGCCCGCCATGCCTGGCTTC GACTACAAGTTCCTGGAGAAGCCCAAGCGACGGCTGCTGTGCCCACTGTGCGGGAAGCCC ATGCGCGAGCCTGTGCAGGTTTCCACCTGCGGCCACCGTTTCTGCGATACCTGCCTGCAG GAGTTCCTCAGGTGCTGGCCGGGGAGCAGGGGACAGCGGGGGCGGGGCGGGGCGGGGGGC GCCGCCTGGGGAGGGTCTCGGGCCCGGGGCAAGGCGGGCCTTTGTCTGCGCTGCGACCCT GTGACCTCAGGGGCGCCCCGTGACGTCACGGGGAGGGATGACGTCAAGCCCCGAGGGAGG CCCCCCCCGCAGGAATCCGAGGGGTCCGGGCGGGTCCCAACTGCCCGGCCCGGGGCGGAA GACCTCGGCGCCTTCTCGTGGGGTCAGGAGGGGAAGAGGCCCTTCCCCGTCACCTGAGAG CCGGCGCGGCCTCAGCCTTGAACTTTGAATCCTGGGGGAAGAGGACAAAACCCGCTCCCG CGTGGCAGTTTGAGCCTCCGGAGCTTTCCCCCATCTAACCTCTTCTGATTCTTCGAACGT TCAGAGAACGGTAGCTATTGTTCTCCCATTTCACAGATCATGAAACGAGATTCAAAGAAA GGCTGCGACTTGCCCAGGGTCACATAGTTACTTAAAGGCTTAACTAGGATTTAAACCCGG ACTGCTTATGATCACACAATGGAGGAAGGACTGAATCCTCCCCCGAAGAAGGACCCCTCT AGGCGGCTCCCCTCTCTCCCGGGGGCTGGAGTAAGGCGGGTGGTCCATAAGTCATGAAGA AGGGGGTCGCACTCGTGTTGTTACTGAACTCCCGCTGCCCTCTCAGGACGCAGGTTAGCC CTTGGCTCTTGGGCATCCATCAAGTTTCTGGGCGCCCTGTATGTCTTGAATCTCCTGCTC ACGCAGGGAACCCCTCAGGCCCGGGTGTGGGAAGCAGGGTGAAGGAGCCCCGACTCTTCG GAGGTCATGCCCCCAGAGCGCAGGGGAAGGCCGAGTCGGCCACTGCCTGGCTGTTTGCTG GGACGAGGGGATCGAGGGCCTGGCAGGGATAGTACCTCTGAGACGCCTGCCTCCGGTGCT CCCTCCCGCCGTGCCTCCCTCCCTCGCTCGGTCCTCCGTAGCTCCTACTGGCGGAAATCT CAGCAGGCCCTTTGTTTTCTGTTCCCCACAGCCTGGGCCGGCTCCTGCCCTCACATATGC TCCGGCACAAGCTGCAGGACTGCCCCCTCCCCCTCGGCAGTGTACACATTTACTCTCCTA CAGACACAGCCCCATTGTCTCCGCCACTGCTCTTCCCCGGCCCTCTGGGTTCCAGATGAG GCCAGCTGAGCCCCCCGACCCCCCCACAGCTGACCCACCCTGACTGCCTCGGGAAAGGAG CGGGGGAGGGGGCCGTCAGGCCGGATTCCTTCCACCACCTTCTTGGCCCCCCTCTCTGCC ACTCCCCCTCCCGGAAATCCCCTCTTCCTCTCCCACTCCCACACCCCCTCCCCCCATCCT GTCTTCTTCCCTGGGCCTTGGCCTCCACTGCACAGCCTGGAGCAGCCTCTGCCCTGCCTG TCCCCCATCCCCCAGTGCCTGAGCTGTGCTGCTGAGGCTTCTGAAGGGGAGAGAGGTGGT TGGGTGGTCCCTGCTCCTCACCCGCCACGGTACAAGCACAAGTGAGGGTGTCCACAGCCC TGGCTGGGCCCCAAGCTGCAGGCTAAGCTTCTGCCTGAAGCCTAGGGACTTGCCTCTGTC CCCTCCCTTTCTCCAAAACCACTCAGTCAGCACATTCCTGAAGCAGCCAAGTGGACCCCC TCCCCCTGGGCCCACCCCTCTTTCCCCACTCCTGCCTGAGCTGTTAGGTTGGCCCAGGAA GGCTGGTTGCCCTGTGGGCAGACACACCCCTTCAGTGCCTGTGGTTGTATTGTCCTTGGC ATTGAAGCATGGCCAGTGGTAGTGGGATCAAGGGGAGGAGGTGGGTGCTAGAAATCCTTG GGGCAGTTGGGGCATGGACTGCCTGGGTCCTGGAGAGTGCCTCTAGAACTGGGCTCCCAT GTGGGCTCTGGTTCCGCCTGGATCCCTGCCTGCCTTCCACCTACCTGACTCAGACCTGCC AGGAATGCCCTGCCCCAGGGCCCTGAGTCCTGCTGGGTGAGCCATTGCTCTGCCTGAGCC ATGCCAGGCATGTGTGACTGGCCCTGGCTGGGGTCAGCAAGGGCATGTCGACAGAAAGAA GCATGCCAACAGGCTCCTTGGGTGCTGACGGCCAGGTAGGGTTTGGTGCAGGAGAAGGCG GGCAGCTAGCAGGAGGGGACGGTCACCAGGCTTCAGAAGCCCACTGAGCAGTGCCCAGAG TCTTAGCTGTGCTTGCTGGACATTTTTCCTTGCCCCAGCTTCTCTTCCTTGTGTGTGTGG TGTAGTAGAGCCTGTCTGAGCTGTGGAGTCAGACACACATAGCCAGGTGCTGCTTCACCT GTAAGCCTCTTCGTTTCATCTGTAAAATGGGGGCATTCCACCCCTTCTCAGAGGCAGGTG GCAAGGGCCGGGTGGGAATGTAAACAGGTGCCAAGGAGCATGCCTTTCCTCCCCTTTTCT GTGGGAGACACACCCTCAAAGGAGCAGGGCAGGGTAAGGTGGCCGCAAGCTGACCTTTGC CCTGGTTCTTGGCAGAGGACCTTCCTGGGGACTGGGCAGCCTTCGCACTTAATCTCAGCC CATCCCTGTTCCCCCTCCCAGTCAGCTTTCAGCGCAGCCAATGAAAACTAACCTAGGGGG AGGGGGTGACTGTGCAGCGTGTTCCTTTCCCAGTCCAGCTGCCATCCTGGGGGAGGGGGT GCCAGCTGCCACCTGTTGGCCAAGTCCTGACTGAGGCAGCTGTCTGTGCCTCCTCTAGGC CCAGACCCCCCTTCCCAGGACAGGGGCTGGGGTCTTCTGGGATCCTGGGGAAGTAGAGCC CCTCAGGCCTCTGCTTGCCCTTTTGTCTCATCTAGGCTGGTTGGGAACCGGTCTGGTGAG GAAGGGAGGCTGCCTCAGTGGAGGGGGTGGGGCCAGGCCTCCCTTTCCCCTAATGAGAAA CCTTTTTCCTGCCCCTCCCCCATTTCAGTGAAGGAGTCTTCAAGTGCCCTGAGGACCAGC TTCCTCTGGACTATGCCAAGGTGAGTCCACACTGCCAGGAAGAAGCCCAAGCACAGTCTG TTGCCCTTGGAGGCCGGAGCTGCTGGCAGCCAGTGGGCTCAGGGCCAGTGTCAACCAAAA GCCTTGGGATGGTGCGCCTCCACAAAGGTAGCCTGTTCCCTCCCACCAGGCCAGTTTGCA AACGAGGCCCCTGTTTGCCCTGGAGGGCATGCACAATGCCCAGCCTGTAGGGGTGCACAG AGCTGCTCTGTGCCCGCAAGAAGTGTTCCCTCCCCTTCCGGTGGCAAGCCAGACCTGTGG CTGAGGGCCAGTATCCCTCCACCAGGGGAAAGGAAGCAGAGCCCCAGGGACAGCCTGGGA TTGAGCAGGCTGATTGGCTGCCTCTTCAAAGGAAGCGTCCTGTGCAGGCATGTTAGGACC CAGCATCAGAGCAGATGCTGCCTGCTGTGCCCTTCATCCCTGGACTCAAGAGGGGCAAAG AGCCCAAGAGAGGCTATTACAGGCTCCAAGGTAGAGCCAGCCCAGTTGGGTCTAGGGGTG GGAACTGGGCACTGCAGTCAGCTCTGACCCTGGCCAGTTCCCCCATCCCTACCCCCAGAT CTACCCAGACCCGGAGCTGGAAGTACAAGTATTGGGCCTGCCTATCCGCTGCATCCACAG TGAGGAGGGCTGCCGCTGGAGTGGGCCACTACGTCATCTACAGGTGAGGCTCTGATGTGA GGGCTGGCACCACCTCTCCCTTGGCAGGCACTAATTGCAGCCTTCCCACCAGGGCCACCT GAATACCTGCAGCTTCAATGTCATTCCCTGCCCTAATCGCTGCCCCATGAAGCTGAGCCG CCGTGATCTACCTGCACACTTGCAGCATGACTGCCCCAAGCGGCGCCTCAAGTGCGAGTT TTGTGGCTGTGACTTCAGTGGGGAGGCCTATGAGGTGGGTGGGGTCTGGCTGAATGTGGA GGAGGGGGTACCTGATGGCCTAGGCATCTCTTAACTCAGCACCTCTGACATTTCCAGAGC CATGAGGGTATGTGCCCCCAGGAGAGTGTCTACTGTGAGAATAAGTGTGGTGCCCGCATG ATGCGGCGGCTGCTGGCCCAGCATGCCACCTCTGAGTGCCCCAAGCGCACTCAGCCCTGC ACCTACTGCACTAAGGAGTTCGTCTTTGACACCATCCAGGTGAGGCCTTCCCTGAACTGT GGGTTGCAGGGTAGGTGACAGGTAGTCAGGATATTGACTCCTGCCTCTCTACTTCTGTGG CCCCAGAGCCACCAGTACCAGTGCCCAAGGCTGCCTGTTGCCTGCCCCAACCAATGTGGT GTGGGCACTGTGGCTCGGGAGGACCTGCCAGGCCATCTGAAGGACAGCTGTAACACCGCC CTGGTGCTCTGCCCATTCAAAGACTCCGGCTGCAAGCACAGGGTGAGATGCCCCTTTTCC TGTCAGCCCCCTTTTGCCCTTGAAGCCCTAGACAGAGGCTCAGCTTCTGATGTACTTAGG CCTTGGTGGTCCCTGCTGTGCTGCTCTGAAACCCTCAGTCCTTCCCTCTGCTGCCAGCTC CAGCCTCTTCCTAACACCCTCTGTCTTCCTCACGTAGAGCTGGGTGCCTGCTACCCTGTA CCCACTCCTCTCCTCTCCCTGGACCTCCCCCTACTGATAACTCTCCTCCCTTCCCCCATG GCCTGGGGCTTTGCCAACAGTGCCCTAAGCTGGCAATGGCACGGCATGTGGAGGAGAGTG TGAAGCCACATCTGGCCATGATGTGTGCCCTGGTGAGCCGGCAACGGCAGGAGCTGCAGG AGCTTCGGCGAGAGCTGGAGGAGCTATCAGTGGGCAGTGATGGCGTGCTCATCTGGAAGA TTGGCAGCTATGGACGGCGGCTACAGGAGGCCAAGGCCAAGCCCAACCTTGAGTGCTTCA GCCCAGCCTTCTACACACATAAGTATGGTTACAAGCTGCAGGTGTCTGCATTCCTCAATG GCAATGGCAGTGGTGAGGGCACACACCTCTCACTGTACATTCGTGTGCTGCCTGGTGCCT TTGACAATCTCCTTGAGTGGCCCTTTGCCCGCCGTGTCACCTTCTCCCTGCTGGATCAGA GCGACCCTGGGCTGGCTAAACCACAGCACGTCACTGAGACCTTCCACCCCGACCCAAACT GGAAGAATTTCCAGAAGCCAGGCACGTGGCGGGGCTCCCTGGATGAGAGTTCTCTGGGCT TTGGTTATCCCAAGTTCATCTCCCACCAGGACATTCGAAAGCGAAACTATGTGCGGGATG ATGCAGTCTTCATCCGTGCTGCTGTTGAACTGCCCCGGAAGATCCTCAGCTGAGTGCAGG TGGGGTTCGAGGGGAAAGGACGATGGGGCATGACCTCAGTCAGGCACTGGCTGAACTTGG AGAGGGGGCCGGACCCCCGTCAGCTGCTTCTGCTGCCTAGGTTCTGTTACCCCATCCTCC CTCCCCCAGCCACCACCCTCAGGTGCCTCCAATTGGTGCTTCAGCCCTGGCCCCTGTGGG GAACAGGTCTTGGGGTCATGAAGGGCTGGAAACAAGTGACCCCAGGGCCTGTCTCCCTTC TTGGGTAGGGCAGACATGCCTTGGTGCCGGTCACACTCTACACGGACTGAGGTGCCTGCT CAGGTGCTATGTCCCAAGAGCCATAAGGGGGTGGGAATTGGGGAGGGAGAAAGGGTAGTT CAAAGAGTCTGTCTTGAGATCTGATTTTTTCCCCCTTTACCTAGCTGTGCCCCCTCTGGT TATTTATTTCCTTAGTGCCAGGAGGGCACAGCAGGGGAGCCCTGATTTTTAATAAATCCG GAATTGTATTTATTAATTTGCTTCCAGCCTGACTTACCTGGGTTGGTTAGGTCCCTGGGA GGCTCAACCAAACTGAAGGCAAAGAAAGGACCAGTCAGAGAAGGGCCGCTGCCTGGGTCT GGCCCCAGGATCCAGCTTACCTGCTGGCTCGCCCTCTGATGGACGCCGGGAAAACTGCAT CGGGCTTTGTGTGGAAGACGGTCCCTGCCACTGCCCTCTGCCGATGAAATGCGGGAAGTG TATGGCCTAGATGTTTCATAAGGCTGGAGTCCCTGGTCAGCCCCACCAGATTAGTGCTTC TACCCTAGGCAGGGCTTTCTTGGTCTAATGGTAATAAGCACCGACACTGCTAAGCACTTT ACGTGCATTATTATTTCATTGAAAAGAACTGTCAAGTGAAATACTTTTTAGCACAGTAAC TGGCTTTGTGGGCTCTAGAGAAGAGTTAATGAGGCAGTGCATGTTCTTGGCCCAGAGTAA GTGCTTAGTGAATGCTTTCTAACTCCGAACCCCAGCCACATCCAGGGACTGGGTGTTGAG CAAAAGGGGCCTTCAAGATGTTCAAGGCACTTGGATTTTCTCCTGTCTCTCATCGGCTTT TCTTAACGGGCCTCAGTGGGTGCATGTGATTATCCACGTTTCACCTATGAAACATGAACA GAGGAGACTGACTTATCAGTGATTCTTCCGCGGGTTCGGACAGGGCCTCGATTCTGTTTT AAACTCCAGTAGTCCCTAGAAATTGTAGCTCCCTCTAGTTGTGGCAATAGGTGTGGGTCC TTGTGCTTGCTTTTGGCAAGTTTCTGAGCTACACAGGGCCTCCATTACCGTCACTGGTGA AATGCGGCTCACCTCCCAGATTTGTTGTAAAGATTAAATGAACTGGTCAGCACA OMIM ID 602464