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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for EIF5B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9669
Official gene symbolEIF5B
Full nameeukaryotic translation initiation factor 5B
Aliases,DKFZp434I036,FLJ10524,IF2,KIAA0741,
Gene summaryAccurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q11.2
Gene position99953834 - 100016728  Map Viewer
Gene orientationplus
Gene size62895 bp
Gene sequence
OMIM ID606086