| Entrez gene ID | | 967 |
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| Official gene symbol | | CD63 |
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| Full name | | CD63 molecule |
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| Aliases | | ,LAMP-3,ME491,MLA1,OMA81H,TSPAN30, |
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| Gene summary | | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq] |
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| Location | | Chromosome: 12 Locus: 12q12-q13 |
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| Gene position | | 56122910 - 56119230 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 3681 bp |
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| Gene sequence |
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| OMIM ID | | 155740 |
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