Entrez gene ID | | 970 |
Official gene symbol | | CD70 |
Full name | | CD70 molecule |
Aliases | | ,CD27L,CD27LG,TNFSF7, |
Gene summary | | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19p13 |
Gene position | | 6591163 - 6585850 Map Viewer |
Gene orientation | | minus |
Gene size | | 5314 bp |
Gene sequence |
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OMIM ID | | 602840 |
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