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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DOCK4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9732
Official gene symbolDOCK4
Full namededicator of cytokinesis 4
Aliases,FLJ34238,KIAA0716,MGC134911,MGC134912,
Gene summaryThis gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q31.1
Gene position111846462 - 111366164  Map Viewer
Gene orientationminus
Gene size480299 bp
Gene sequence
OMIM ID607679