Entrez gene ID | | 9733 |
Official gene symbol | | SART3 |
Full name | | squamous cell carcinoma antigen recognized by T cells 3 |
Aliases | | ,DSAP1,KIAA0156,MGC138188,P100,RP11-13G14,TIP110,p110,p110(nrb), |
Gene summary | | The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q24.1 |
Gene position | | 108955165 - 108915991 Map Viewer |
Gene orientation | | minus |
Gene size | | 39175 bp |
Gene sequence |
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OMIM ID | | 611684 |