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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CD81 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 975 Official gene symbol CD81 Full name CD81 molecule Aliases ,S5.7,TAPA1,TSPAN28, Gene summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. [provided by RefSeq] Location Chromosome: 11   Locus: 11p15.5 Gene position 2398547 - 2418649  Map Viewer Gene orientation plus Gene size 20103 bp Gene sequence >CD81:2338547..2358649:Length=20103 GAGCGAGCGCGCAACGGCGGCGACGGCGGCGACCCCACCGCGCATCCTGCCAGGCCTCCG GCGCCCAGCGCCCCACGCGCCCCCGCGCCCCCGCGCCCCCGCGCCCCTTTCTTCGCGCCC CCGCCCCTCGGCCCGCCAGGCCCCCTTGCCGGCCACCCGCCAGGCCCCGCGCCGGCCCGC CCGCCGCCCAGGACCGGCCCGCGCCCCGCAGGCCGCCCGCCGCCCGCGCCGCCATGGGAG TGGAGGGCTGCACCAAGTGCATCAAGTACCTGCTCTTCGTCTTCAATTTCGTCTTCTGGG TAAGGGCTGCGCCGGGGGCCGGGGCGGGAGGGGGCAGGCACACACTCCACGTTGGGCAGG TCCCGCGGCAGCGTGCTAGGCCCCGCGGGCGCAGCGCGGGCCGCGAAGTTGTGGGGCCAC CTGTGGGCTCCAGGAGCGGGGTGGGGGGTCGCCCGGGGCCACCGCGCCCCCCGACATTGG GGCTGAGGGCTGCGAGCCGAGTTTCGGGGCCTCTGTGCTCGGGGGCCCACCTCTGCGGCC GGGCCGGGGCTTCTGGGGGCCGCCGGGCAGTTCCCGCTGTGGTGGTGATGGGTGCGGTGG TCGCGGGTCGGGACCCGAGTACCCGGCCGCCCCTCAGCTAAGGAGGGGCCTGCGCGGGTC CCTGGCCGCGGATTCCGGACTGCTGCTTCGCGGGGACGAGGGGGGGGCTCGCGGGCGGGA CTCCTGGCGCCCCGCCCCCATGAGCTCATCAAGAGCCGCCGCCCCTGGATGGTGGGGCGG GGGCGCACACTTTGCCGGAGGTTGGGGGCGATCCGCCTCACTCTTTCCCCAGCCCAGCTC ACTCTCCAATCTGCGGTCACCACCCGAGACCTTCCTGGGGGTCGCGCCTAAAAGGAGCGC AGACTCCCGCCGGGATGGCCCAGAAGCTGGGGTGCGCGCACCCTGGCCGTCCCTGCCTGG GAGCCGATCTCCCTCTCCTCACCCAGACACGTTCCAGCGGAGGCCTCCTCCCAGAAGGGC TCTGGAGGCCTCGCAGGAGTGGGGATCCCGCGGTTCTGAGTTGGCACAAGGAAGAGAGTG GCACCAGGGGCCTGGAGTGGATGGCAGGGTCCGGGAGTGGGGCCGCTGCTTTGCAAGAGG GGCCCCCACGCTGGGCATCTTTGGGTGCCAGCGTGGGTGGAGGAGGGTCTTTTGCTGAGA ATGGCTTTCTCCTGACCGCAGTCTTTGCTGCTGGGAAGTGACTGATGGGCTTTCGCCTTT TGTTTCCATTTCCTGTCGGTGTTAGAATTGGGGAGGGGGTGGAAATCCCTTCTTGGCCTG GAAGGACTGGAGTGGGTGTCCATGGCCGCGGCCTCCCCGTGGCCACGCCCCTGGGCATAG ACTGCAAGCCCCTCCCCGTGCCCCCCAGGCTGTCACCCCCTTCTCGTGGAAGACTCGGCT GATGTCCCAGTGGACCGAGTGTTTCTCAAGTTGAGGCAGGGAGGGCAAACTTTTTAAATG GCCCCTGGAGCCAGTGTGTGGGACCAGAGACATCTGTTTCCCATCTGGACGGCTGAGGAT CCCAGTGCGGATGATTATTTGGAGGGGGAAGGACGGAGGCTGAACTGAACTCTCAGCTGG GAGATGAGTGGGGCAGTCACATCCCACCTTCCCCAAGCCGGGCTGTTCTGCACAGCCTGC TTGGGACGCTGGTGGGAGTCACTGTGGCCTTCGGCACTGCCCTGGCAGTGGGGGCAGCTA GGCCATTTGGGAGGGGCTCGCCTTCCCCAGGCCCGGCCCTGGGACCTCAGCCGTTGCTTA GTGGTGGCCTGCTTCAGCCCAGGCATGTGGGAGAGGCACCAGACACAGGATGTCCCTCTG CCAGCCCCTGAAGCCCCGTCCCCTGACGAGGCGAGTGTGGACCTGGGGGTGGGGGCTGAG GGAGACTGTGGACCTGGGGGTGGGGGCTGAGGGAGGGTGTGGACCTGGGGGCAGGGGCCG AGGGAGGGTGTAGGCCTGGGGGTAGTAGGGGCTGAGGGAGAGTGTGGACCTGGGAGTAGG GGCTGAGGGAGGGTGTAGGCCTGGGGGTGGGGGCTGAGGGAGAGTGTGGACCTGGGGGTA GGGGCTGAGGGAGAGTGTGGACCTGGGGGTGGGGGTTGAGGGAGGGTGTGGACCTGGGGG CAGGGGCTGAGGGAGAGTGTGGACCTAGGGGCAGAGGCTGAAGGGGAGTCACGGGAGGGG ACTTCTCCGGAGGTGGATTTTTGCTCTCTGGACGGTGTGTCAGCACTGGGTGAGCCCCTC CTGCCTGCCCAGGCTGAGAGGTCTCCCTGGCAGCCCCCTGGGAGTGTCGCCAGGGCGGGC CTGGAAGTTTCCCAGGCAGCTGGGGTGGAGACCTGACACATCCCAAGGGTGCTTGTTATT AAGGCTCAAGGAAATGTCTCTGAGGCCTCACCGCTCCTCTCCCCAGGGCCTGCTCCCTGC AAAGCATTGAGAACTGAGTCCGTCCACAGTCACTGTGGACCCACCCATCCACTGGGGCTC AGTGGTAGCCAGCAATGCCAGGCTGGGTGAGGTGGGGTTGGTGGGCACCACCCTGGTGGA CCCCCCTCCACCCTGGTGTCGCAGGGTGTGTGGCTGAGAGCACAGTGCCATGGGCTTGGG CCTCCTTGGTGGAGTCCCCAACACACTGCTCTGGTCCTGGGCCTCGGCCTTCCCCGTCTG CAGTGGGGGCCCACAGTGAGCCTACCTCCTGGTGGTGTTGGTGGATTTGCTGACATGCCT GAGTGTTGACAGGGGGCTTGGTGCAGGAAGGGCTCAGGGCGTGGGTGTTGGCCAGGGGTC CAAAGGGACCTCTGCCTCAGAGAGCCCAGCCCAGACAGGCAGGATGTGCAGTGGGGAAGG GGCTGCGGGAACCCTGCAGGGTCCAGAAGGACACAGTGCAGTCCTGTGGGCTCTGGGGAG GCTGGTGGGGAGGAGGTTGACAATGGATATCTGGGTGGGGCACTTGTTAGAAGTTCCATT TTAGAGAGGAAAGAGGCCTTGCCTGTGGGAGAAGGCAGCTGGGGTAGCCTGACCTCTTTC CCAGGAAGGAGCCCACACACACACGCACAGGCACTCACACACACGAATGTGCACACACAC ACACTCCCACCTTCACACACACTCACACTCTTGCTGTCTCCCTTCCCAAGCCAAGGTGCG AGGGGGAAGGTCTGGGCAGCATGCACCTGCGCCCTGACCGCTTTGGGGGCCAGTGAGAAC TGGGCTCCCTGGGTGCGCGGCGGGCCCAAGCAGGGAGGACATTGCAGATGCCCTGGCCAA GCAGCGTGGAAATCCTGTCCCTTGGGTGGGTCTCGGAGCCTCCATCAGAGGCGGCTGGCA CCTGAGACCCACCTGCTGCCAGGAGCAGGGCAGGAGAGTTTGTGTCCCGGGACAGGGAAC TGGCCTGTGGGAGCCTTGCCTTCCTCATCTGTGTAATGGATATAAGAGTCTTCTCCTCGG GGGCTGGCCAGGGAGTCCAGAAGAGGTGTCACCAGTCCCCGCAGGGAGAAGAGCGGTGTC CCCCGCCTGGGACTGGCTGCTCCCCCAAGCTAATGCAGCTGGTAGCCACCTCCCAGTGGC AGGGCAGCCAAACCCGGCCGGGAAAGAGACTGATTAGAAGCCTCGCTCACGGGTATTTCT CGCTTCCAGACAGCACATGACTGTCATTTGGCACGTCTTTCGCCGTCCTTCCGGGAGAGG GGCTGCAACCCTGGCAGGCGCTGTGGGGGAGGGGGCTAGGACATCCTGTGCCTGGTTTCA CCAAGTGGGTGTGTGGACTTTCCCTGGCTCCCCCAGGCTGTCTGGCTGCACAGCTTTGGG GAAACGGCCACTGGGTCAAGCGGGCCGAGAAGAGGAAGTCTGTGGTTTGTCTCTGCTACA GACTGGCCCCAGTGAGGCTGTCCAGCAGTGCAGGGCACAGAGCAAAAGCAGGGAGGTATG GGCCTACTTCCCCGGTCGCCCCTGTGGCTGGCTGTGGCTCTGCCGGGTGCTGACAAGTCA CTCGCCCTCCCTGCGGTCACCAGGGTGCATGCCCGAAAGCCCTCCATTCTTTCCTGGGTT TGAGGGTCCTTCTCCTGCACCCACCCCAGCGCCCAGTTCAGCTCAACTTTCAGAAATCTG GTTCACCCCCAATCCCTTTCTCATAACTGCTTCCAAGCCCAGACAAGGAGACAGACCCCA AAAGATCCCTACCCCTATTTCCGCACCTGAAATCGCACCACGGGAAGAGCTTTGCTCATA GAGTCAATAAGGCTTAGAGTCCAGGCGCCTGTGCGAGGGAGCAGGTCATCACCCTTGTAC CCACCGTGGTTTTAGACAGGACCCTGAGGTTGGGGTGGGGCTGGGGCTGGAGAGGAGCCA GGTGCCCTGCCCCTTGCTTGGGCCCCGTGTCCCTGTGATCCAGGCTGGGCGTGCTATGGG TGCTGGGTGATATTCCAGCCCTGCAGGTGTCCGCCTTGTTCCCAGCACCCCTCTGGGCAA GAAGAACCAGGCTCTCCCAGAAATGGGCTTCAGTGATCTCCACTTCCAAGTCGTCCCCAC CTGCCTTGTAGGACACAGTGGTACCTGGTATGCTGGGCAGCCTTCCAGGAACCTCTGGAC TTACTCAGTGTCCCCCAGCCCTACACACCATTCTTTGTGTTTCTGGGCCCAAACTAAGCC CCCCAACCTGGGCTGCAGAGCAAGTGCTGAATCATGAGAGACCCTTGAGGGTCCTCCAGG TAGGCCCCCAGTGCTGGAGGAGTCCCCTCAGGCAGGGGGCCACGCCCAAGGGTGTGGAAG GTCAGCTGGCAGCCGGATCTCACTTTTGGGGCTGTAGGCTTCCTGCACTGGCCGCCAATG CCATGGCCGTGGGATGGCCAGGATAAGGCATCTGCCCCCCACCCCCACCCCCCGCACAAG GTCTTTGAGGGCTGCGGGCTCAAGGAGTTGGCGGTAGGGCTGGGGGACCAGGGGCACAGA GCTTGTAAGCGCCTCTCTCCAGGATGTGGGTGGCCCAGCAGGGGAGCTTTGAGAGTCCAG GTGTGAGATTCCAAATGCTAGGGGCCTGAGAGGAGGGAGCCACCAGCTTGGCCAGAGCCT GGTGGATCACGCCCCCACCACGCCTTGCCCTTCTCTCTGGTCATGTGCTCTCCCACCACG TTTGGAAAGTTACTGCTTCCCTCTTCCTCAGCCCCTCGGGCTCCCAGTTATGGAAGTGGC GTGATTCAGAGAAGGTAAAGGATGGGAGGGAGAGGGCTGGGTGATGGGGGACCCCGCAGG GCGCCCTGTGCTGTTACATGGAGCTCCAGGATCAGGGCAGGTGGGCAGCCTGGGGTCCTC ACTTCTCTCCCCAGCCAGGCCAGGTCCCTCACAGCCCTGCCAGGAGCATGATATCCGCTG CGGTGCAGAACTAATCTCAAAGCTCAAACCCAGGTAACAGTGTAGGTAAAACAGATGACA GGGCATGAGACTCACCCCAGGACAGGCGAAGGACCCAGGCCGATGGGGGCCCAGAACAGT CCTGATCCTGGAGCTCCTTCCCGAGTGGGACCCCAGGGGTTTCCGAGGGGCTTAGAGTAG GGCTTAGAGGCTTAGAGTAGGGCTAGGGACTTCCTGGCTTCCCTGCCTCGGGAACAGCTG GTCCTGGAAGGGGCTTGGTCCTCGGGGCACTGGTGCCCACCACCCCTGATGCCTGGGAGA CACCAGCATCCTCTGAGCATGTGTGCGTCCTCCTGGTCCCGAGGGAAGTGACTCCTCACA TCCCCCAGCTGGCGGGGCCAGAGGGCCAGCATCCTCGCCTGACACCTATTTTTAGATGCT GAGACAGGCGGCTTCCTCGGGGCCAGGGGCCCTGTGAGTGGAGCTTCCGCTTCCTGGCCT AGGAGAGAATTCCTGCTCCTCTTCCCTCCATGCTGCCTTTTCGCCCCTGGAGGCCACAAC GGGGTCAGAGGGGCAGCTGCTCACCACCTAGGAGGGCCTGAGAGGGCCCTACGTCACCCA GGGAGGAGTCTGGCCCCGTCCCCAACCTCCACACCCAGGCCTGGCACTGCCCCTTCTTGG TGGGCAGAGAGTGAGGGGTTGGCCTGCAGGGACCCAGGCTGGAGGGGCCGTTCACCTCCG GCCCCCAGCGTCCCTTCCTGGAAGCACCTTGGTGAGCCCCTCCCCTCCTTCACCCAGTAT CTCCAGGGGTACTTCCTCCTTTCCTTCCTGCCTCAGGGCCTCACTGTCCTCCTGGGGAGG GTGTCTCAGGCCCCAGCACCTCCCAGTGGCTGAGCCGAATGGGCACTTCCCGGTGTGTTT CCCATATGTGCAGTCCCTAGGTGTCGGTGAGCAGGCACAGAGCCCGCAGCGTGGCCCTGC CTGGTGGACCCCCTCCCCAAGAGCATCAAGGGAGGGCCTGGACTAGAGACACACAGATGC CCAGCCTGTACGTAAAGGCGGGTGAGCTGATGTACCATCGTCCTCGTCCCCCACTGGGGT GCCTGGGCAGGACTTGGGGTGACCACTTGGCCCGTCTGGGTGGGGGTAAGGTATGGGTGG GGCGACCAGATCCCTGCCCTTTCCTGCAGCTGTGGGGGTGTGTGTGCTGGCCTGGAGAGC TCCCACCCGAAGTTCTGGCTCCTGGCTGTCCGGGGCCTGCGGGGGCAGCGAGCAGCTGGC ATGGGTAGGGGAGCTGACCTAGGCCTGCCCGGGCAGCGCCTGCTGCCTTTTGCTCCCTTT CAGCTGCTTCTTGGAAACAGCGGACAGGCTGGGCAGGAACCCAGTGTGCTTGGCAGCCCC CCTTTTAAAGTCGATTCTGTTATTTATTAATTCCCAGGAAGGAGAAAGAAAGAAACAATC CTTCATAGAGTACAAACACTGCTTTTAGTAGCCTTGCAAGGAGCCCTCCAGGAACCCCAC AGGTTACCTGGGCTCCATCCTGAGAGCCACCCTCCATCCCCAATCCCCAGCAGAGCATCT TGTGGGGTGGGGCGGCTTGTGGGGCGGGGCGCCTTGGGAGGCGGGGTGTCTCGGGAAGCG GGGCGTCTCGGGAGGTGGGGTGGCTTGTGGGGTGGGGCATTTCCTGGGGTGGGGCGTCTC GTGGGGTGGGACAGCTTGGGGGGTGGGGCATCTCGGGAGGCGGGGCGTCTTGTGGGGTAG GGCGGCTTGTGGGGTGGGGCATCTTGTGGGGTAGGGCGGCTTGTGGGGTGGGGCATCTTG TGGGGTGGGACGGCTTGTGGGGTGGGGCATCTCGGGAGGTGGGGCATCTCTGGGGCCCGG CCACTTGGGAGGCGGGGCATCCTGGGGGCGGGGCATCTCAGAGGGCGCCTCCGGAGGCTG GAGTATCTTGGGAGGTGGGAGCAGGTGGCAGAGAGGCTTCCCACAGGTGAGCTTTGAGCA GGGAGGTGCCTGTATGGATGGCTCTGTGGGGAGAGGGGTGACAGGAGTTCCAGATTCCGG CACTTATGAAACCTCACAGTGATGGAGAGCCGAGTGCTGCTGTGCAGGCTAAGTTGTGTG CATGTCAGCTTCTGCACTTTTATTTCCTTGTTTGTAGACAAGGCAGAGAGAAGCTGAGAT GGGCCTGAGGTCGCCTTGGTGAAAGGCACTCAGCAGCCAGGGCCTTGGGCTGCCCTCCCT CATCACCGTGAAAGCGGGACTCTCTTTTAACTGACATCGGGCTCCATAGTTACTCCAGTC CTAACTTTGATGGATCCTAAAAGTGCACTTCTAAGGACGCGGCTTCGGTGTTTCCCATGC CGCTGCTTGCCCCTGGGAAGCGTTGGCTCTGCCTCGGAAGAAGTTAGCGCCAAGATGGCA GCCTGGGGTCTTTGGGGCCCAGAAGAAACACTGGCCCCGGGGAGTTCAGTCATCAGGGAC TTAGGATGTGGGGGCTTTTCAAACAGCTTTATTTAGACGTGATTGACACACAGTAAATAC AGATGTTTAAGGGTACAACTTGGTAAGTTTTGACAAATTTATACCCCCGTGAAACCATCA CCAACTCCCCAGGTGCCCCTGGGGCCCTTGGGATCTCTGCTTCCTGCCCCTCCTCCCCGT CCCAGGGCAACCACGGGCCGTCGCTGTGGGTGCACACAGCATGCATTTCTTCAACAAGCG GACTCAGAAGGCACTTGCACATCGTTGCTGTTCTGCCTCTTTGCTTCAGCATGATTACCC AGAGGCGCACCCGTGCCGTGGCCTGCCCGTCGTCTATGCACCCGTGCTGTGGCGTGCCCG TCGTCTGTGTGGCATGCCTGTCTGTGCACCCGTGCTGTGGCGTGCCCGTCGTCTGTGTGG CATGCCTGTCTGTGCACCCGTGCTGTGGCGTGCCCGTCGTCTGTGCACCCGTGCTGTGGT GTGCCCGTCGTCTGTGCACCCGTGCCGTGGCGTGCCCGTCGTCTGTGCACCCGTGCTGTG GTGTGCCCTTCGTCTGTTCCTTTTATTGCCGGGCAGGGTTGCACCCACATGTGCAAGCCA GCGACGGACCCCAGGTTCACCCGTTCACCGGTCAGTGGGCATATGGGTTGTTTCAGTTTG GGGCATTTACAAGAAACGTGCTAGAACATTTGTGTACAAGTCTTGTGTGAACCTAAGTTC ATTTCTCTTGGGTAAATACCTGTGCGTGGAGCAGCTGGGTCATGTGGTGAATGTGGGTTT CACTGCTTAAGCAGCAGTTTTACATAACTGCCAAACTGTTATTCAAGGTGGCTGGACCGT TTTACAGCCCCCGTTGTATGCGTCCCAGTTGCCTCCCCCAGCAGCATGTGGTGTGGTTGG TCTTTTTCGTGGCAGCCAGTCCACTGGGTGCGCTCGGCATGTGGCTGCAGCTTGACCTGG GTTTCCTGGTCCCTGGCAAGGTGGAGCATCTCTTCATGTGCTTTTTTGCTGTGTGTGGAT CTTGCGGGGAAGGGTCTGTTCCTGTTTTTTGCCCATCTTTCAAAGATTGGGTTGCCAGTT TTCTTGCTGTTGAGTTTGGAAAGCTCTGCATACGTTCAGGGCACAGGTCCTTTACCAGGC TCTGCCCCAGGTCTTTCGGAGAGCAGGTGTCTTTCGCATTCCTGACTCTGGGGAACCTCT AGCCCTGCCACATGGGGTTTGTTATGGGGCAGGGGCACCTGTGCCTTTCCCACCACGGGG CTTGGGGATTTGGTGCTGCCATTGCCCTCCCTCGTAGGTGGCCCTAGGGGGGTCCCTCCG CCTCCGTTTCCTCATCCAGAAACCGGCAGTGACCATCACCACCATTGTTGTCACCTAGCT CCAGCTCAAGGTCCCTGCTGAAGGTCGGAGAGCTTGGCATGGCCCCGTTTGTCCATGCTA GGGCTGGGAAGACCAAGGCTCAGGTGAGGCCTCTGCCCAGTGCCTGGCACTCCTTCTTGC CCCATTTTTCCACCCAGGGTGGCTCCCGACTACTTCTGGTAGCCTCGGGGACAGTTGAGG TGGACAGGCTGGCGTCACCCCCATTTCCGGCTGTCCCTCCCACCCCCTCCTGGCCCAGCT GTTCTGCCCTATTAAAAGTCACATGGGCCCTCGGGTCCTTCCTGGTGTTGGCCCAGGCTC TTTCAGGCCCTGCAGGCCAGGACCAGCCTTCCCTGCAACCCTCGGCAGAGGCCTGGGGCC GGGGCTTGTCTAGGGGCAGCCTCCCCATACGGCCCTGGAGTCTGAACAGAAGCCCCTTCC CAGAGCACAGCAAGAAGCTGCAACGTGGCCTGAAGTCCCACCATTAGCAGGTTTGGGGTT TAGGCTGAGCTTTGCCATCACTACCTTTCTGTTAGGACGGTATGCCCATTAGATGGGATC ATCCCCTCAGCGCCCAGGCTAGAGGAGGGGTGGTCCCTGCCCAGCCAGGGAGGGCTGGGG GTGGATGGGCCTCTACAGAGCAGCTTCCGAGCCAGGCACGGTTCCATGATCAGCTCTGTT TTATAGAGGGGGACACTGAGGAACCGGGAGCCTGGGGACCTTCCAGTGGCCCCACAGCTC CTGTGGCTGAGTCAGGGTTTGTCACCAGGCCTCTGTGGGGATGAGGCTCCCCCATCCACC TGCCCCACTCTGTCCTGGAACAGCTCTCAAAACGGTCTCTGGACCACAGTTTCAAAAGAA AATAAGCAATGTTTTCAAAGGCCCTGGAGGAAGCCAGAGTTACCACGGCAACTCTCGGCC TCGCCACCTCCTCCCGCCAGGCTGCATCTGGAGCCAGCTCAGGAGGGCAGCAGGGTGAGG ACAGCCAGGCTCTCTGGGGCCACCCCCCAGCCCCCACCCTTCCTGCCTCTCCTGCACTGT CCACGGCCCTCCCTGTGCTCCCACGGGTATAATGGGCACAGAAGAACCAGGAGCTGTCTG CCCCTGCAGGATTCTGGAAGCCAGGGGCCCCTGGCCTCCCTGGGGCCTTGTCATGTGAGG GGCACACGTGGGGTCCCAGCTGCCACATGGCTTCCAGCGCTGCCCGCAGGTGTATGTTGG GCCCTTGGTGACTCTAATGCACCTTCCACTCGGCACAGAAGAGCTTCAGTCTGGGGCCTG GGCGGGGGAAGTAGGCTGCCATCCTCGCTAAACCAAAGTGTGAAAATTGAGTTGAAACTC CCATAGGAGGGCAGGAGGCACAGCTCCTCAGAAGAAGGTCTGAGAAACCACAGCCCAGGT TGTTGTTTCGGGTGTGTGGAGAAGGTGCTCTGGCAGTCCTGCTACAGGGGGACCATCAAC AGCCCCTTTGGGGTGAGAGCCCCGTGGCTGCTGGCACCAGCAGCCCCTATGAGGCTTATT TTATTTTTGAGACAGGGTCTTGCTCTGTCACCGAGGCTGGAGTGCAGTGGCACAATCATA ACTCACTGTAGCCTCAACCTCCTGAGCTCAAGCGATCCTCCTGCCTCAGCCTCCAAAGGT GCTGGGATTACAGGCGCTTGCTACCACGCCCAGCCCCCTCTGGCCTTATTGTTTGCCAGG CCCAGCTCAGGTCCCGGAGGAGGGGAGACAGGAGTGTGAGGGAAAGGGGGAAGAGGTATA GAGCCCCCAGCTCCTCCACCCACCCGAACCCTCACCGAGGCCCTAGACCCTAGACCGGCC TGACCGGGGGGTCCTCAGGCCGGGGACTTGGGTGCAGGCCATGGTGCTGGGGCCTGAAGC TCACGCTCTGCTGAGCACAGCCCCCTGCCCAACCCCACCCTGGGGCCCTGCTTCCCTGGC CAGGGCCATTGGAACAGGAGTGGGGCTGTCCAGGTGGTGTTCTTGGGTCCAGCCCTCAGT TTCTCTTCTGCAGTTGACCGGCAGCCCTGCATCTGTGGTGGGGTCGGCGCCTGGTGCTGG TGAGGCAAGGCCTCAGCTGCTGGGACAGGACCTGCCTGGCACCCAGCTGGTGGCAGAGCC AAGCATTCCGACTCAGCTCTGGGAGCAGCTGCCTTCTGGGCTGGCATTCTCCGCCAGGGG GGTTGTGCCCTCGTGGCCCCCCCCGGGTGCCTCCTCACCTGGCTGATTTCATCTCCTGTC CCCCTGCCTCCTCCTCCAGGAAGCCCCCAGGGCCTGGCCCTCCTTGAGAGTGGCATGGAG GAGGAAGAAGACTCGCCCAGGCCCATGGGAGTCGGATGGTGGCCGCACTTGTGGGGCCCT GACCCCATAGGCTTCTTCAGCACGCCCTGGCCTGGGTGATCCCTGCCTGAGGGCTGTGCA CGGCTCATCTGCCAGACCAGATTTTAGGGGATTCTTGTACTGTCCTCCTGGAGCAGCAGG GGGTAAAGCCTGACCCACCCAGACTGTCCAGCAACAAGGGCCTCCTGCTGTGGGCCAGGG ACCCTGGAACTGACCAATTGTGTCCTAGGGACGCAGAGTCCCCAGGCTGCTAGAGGGCTG TGGGGCCCTGTTTCATGCCTGAAGCAGGAAGAAACCCCAGGAGAGGTCTGAAGGGGACCC AGCCCCCACCCTGTCTAGCAGGGAGGAGCCTCTGCAAGAGGCCGAGGGGTGCTGAAGTGG AGGAGGATAGAGGCAGCAGGACTCAGGGTCACTGGTCATTTATGGGGATCACACGGCTGC AGTGTGCCCTGCATGGTGCTAGGCACCAGGGACAGCAGAGGACAAGCCTGTGTCCTCTCC CACCACCAGAGGGCTGGGCACTGCCCCTAGGGAGAGAGGGGGCCTTGGTGTGTGCAGAGG GGGGCCTGGGGCACGTGCCTGGCCTGGTCAGATGATCAGAGTGGGCTGGGCTGGGCCTGG TCTGGGGCCCAGTCTCAAGGGCAGACCCCACCTGGCTAGAGTTGATTGTGTGCACACCGG ATGACCCGGCGTTGAAGGCCTCTCCTCTCTGTGAGCCTCATCCCCACCTGCCAGACTCCC AGCACAGCCTGCTTCCTGCCCCAGCTGCTGAGCGACAGCGCTGGGCCGGCTTCTGCGCGC CCCTTCCCCCAGCCCATCTTGGAAACCACAGCAGCGTCCTTCCTCCCAAGTCCCTTCCCA GGGCTGACATCCCACAGCAGGGATGTATCCCACAAACCCCGCAGGCCCTGGTGCCTACAG CTTGGCCTGGTAACATCAAATCCTACCCTCTCCTCCTGGCAGCAAAGATGGGGTGCCCCC ACCCCAGAGTTCTCAGCACCCCCAGACAGAAGCAGTCCCCCAGCGACCTCAGAACTCTTG GGGCGCTGCCACACCCTTGCAGGAGGGGGCAGTGTTCCTGGGATGCTCAGGTCCTGGTAT CACCTCTGGCCAGATACGGAAGGTGAAACTACAGGGCATCCAATTCACCTTGAACTTCAG ATAAACACCAGATTATTTTTTTGTATGTCCCGTGCAATATTTGGGACACACTTACCCTAA AGAAGTATTCTGTTTTCATCTGAGAGGCAGATTTAACCGGCGTCCCGTGTCTTCCTGGCA GTCCTGCCCTGGAGTCACACTCCACAGGTGCAGGGCAGGGCCAGGCTCCAAGTAGATGGC GGCCAAAGCACCCGCCCCATGCTCCTGACTCCCGGGGCTCTTCAGGGCATTGCGAAAACC AGCAGCAGAGCTGACACCTGGTCCCTGCTCGGGAGCCAGCAAGGCAGGAGGCTGCTTAGG CCTTGCGTGTGGGGTGGGCGCACTCCCTGCTGCAGTGCTCTTCGTACATGTGACACTGTT CCCGCTCTTTCCCAGCTGGCTGGAGGCGTGATCCTGGGTGTGGCCCTGTGGCTCCGCCAT GACCCGCAGACCACCAACCTCCTGTATCTGGAGCTGGGAGACAAGCCCGCGCCCAACACC TTCTATGTAGGTGAGTGCACATGTGGCCGCAGACGCATTCAGGGAGGGCTTCTAGGAGGA GGCAGGTCCTAGCCTTTTGGATGGGGACATGGAGGGTGAAAGACAGTCGGGCATGGCGTG TCCGGGCAGGGAGGCGGCCCTGGAAAGGGCTCTGGGCACAAGGGTTGAGATGGAGGTGGG CCTGTGGCCTGCTGGCCCTTCTGGTCTGAGCCAGGGCAGGGGGTGGCAGCTAGGCCTGGG CAGGGACTGTGTGGAGACCTTGCTTATTTTAAGTGTGGGGTTATTTCGGGGGAGGCTCCC TGAGAAGGGTGGGGCTGGATGCCTGGGCCACACAGAGCAGCCGAGGCAGCTGGCGCTGTG GAGCCCGGGAGGGAGGGAGGGATGGAGCTCAAGGGATGGAACCCAGTGAGGGGTGGAGAC GGGGCAGGGGAGGGGTGGAGAGGGGTGGAGACGCCCCAGAGGCGGTGTGACTCAGCTGCC CCTGCAGGCAGCTGCACCTTGCTGCCTTATTAGGCTGCGTGTGGGGGACTGGGCTGCCCT CCCTGCCCCCAGGAGCAGGAGCAGGAGTGATGGAGGAGGAGGAGGGGAGGGGCAAGGCCA GGAGGAGGAGGAGGGCCATCTCACTGTGCAGAGAGCAGCACCCTTCCTCCTGGTGCCCCT GGCAGGGCTGGTGCTGGTGGGGCTCTGGGAGCATTTGTTGAGATGCTTCTGGCCTTGAAA GGAGGCCCCTGGGATGGCTCTGTTGCCCTCACAGGCTGAGGGGTGGGTGAGGTGGGCAGC CTGTGTGTCCCCAGTCCTCAGGGCTTCCCTCAGCCGGCAGGTGCCCCCAGGCCTGGAGCT GCAGGGCCAGGCCCCCTGCCAGTTACGGAGGCTGCTTGGCTTGGTTGCTGAACCAGGGCC CCAGGAGGCCGAAATAGCCCCACACCTGCGCCGTCCCACCTCTTTGTCCAGTCACCCCAG GGCCAGGTGAGGGCCCTGGCCACACAGCGTGCCCGTTCCTTCTTCCCCATGCCCCGCTCA TGGGTCAGAGGGCCGGTGCTGGGGTCCAGATGGTGTCAACAGGGATGGTCCCTGTCCTCC CCAGAGACAGAAGCCTGTGGCCCACGGAGGGTTTCTGGGCCCAGCCGATCCTAGGGAGGG TCCCATGGCCCTGCCCATAGGTTCCTGGCCTCTCTCGGGGCCGTGGTGCCCTCACAGGTG GTGTCAGGAAGGACGGGAAAGGCTGCTTGTCCCAGGGGCTCATGTGGAGACCACCCCCTG CACGCAGCTGGGGCGCTCCTGCCTGTGTCCTCAGAAGCACTCGGCTTAGCTTTGCCCATG TGCCTGGGCTGTGGGTGGCAGAGCCCGGCCAGCATCCTCCGATCTCCAAGGGTGCATCTC TACTGGAGGCCCCTCCTGGGCCTCTTGCTCCCCGCTTCCCAGATCATTAGGATATTTGGG GTCCAGAAGGGCCTCCCAGCCATCCTGGGCCTTGTCCTCCGGGGCCACCAGTCCAGCCAG TGACAACCACAGCATCCCCGGCCTGGAACGAGGCTGCCCCCAGCACGTTCCTCGTACTCC TGTCCAGGGACAGGAGGGGCTGCCCCTGCCACCGAGTCCCCTTCTCCAGGACCTGGGGCC TGTGGGTGTGAGGCAGGTGTTCTTGGAAGGGGTCACTCTCCAGGCACCCGGCGGCCAAGG CTTGTGGCTGGAGCAGCTCCCGCTGTGGGGTCGGCGTCGGGCCCCGTGTGGCCGGAGAGG AGCTGAAGGGTCACTTAGCTTCGGGCTGGGGCGAGGACAGGGGACACCCCAGAGAGGTAT GCCAGGCCTCCTTCCTGCGCCCCACTCTCGGCAGAAGCAGAGGTCACAGGCTGTGCTGAG GCCCCATGGTGCTGCCCCCATGATGCCAGGGTGAGGCTGGCGTTGGAAGCAGGTGTCTGA CCTGCATGGTGTCACCGTGGCCACATCAGAGCTCCAGCCCCAGAGCCGCCCACCCTCGGT CCTTGGCTGTGGTTTCCCTGGGCTGGAGGAGCCTGCCGTTGTGTTGGCCACACGACCACA GGACCTGCCACCCCCGACGTGGGCTCTGCCTGGGCCCCCACTGGACAGGGACCCCTTGGA GCTCCTCTGGCCACCAAGTCCTCGCCCATTCCAGAATCGGCCTTCTGGAGCCTCTTGCTG TCCCTGATGCGGGCTGGGCCTTGCCAAGGGCTTTTTTTCCTGCGCCGGGAACAGGGTGGA TTTGCTGGGCTCACTCCCCTCAGAGACGCTGCGGGTGCGGTGGGTTAGGCCCAAGGGCGT TAAGAGAGGAGGCTGGGGTGGGGCTGGGGCCTGGCAGGGGGTCTGGCAGCCCTGGGCCTC CCACCTCCTGTCAGGACCAAAAAAGGCAACGCGCCTCTCCTGACCTGTACCCCGGAGTGA ACCCAACCTTGCAACCCAGGAGTGTCAGGGCCTGAGGGGAGGGAGACCTGGCTCCTGGGT GCCGTGCCCGTAAGGAGGTGGCCACCTGCAGGGCATTCCTGGCAGAGGCTTCATCTGGCC AGGTAGGAGGCTGGGTGGCCGAGCCCCAAATCTGGGTGTGTTCTCTGCCTGGCGGTGGGT CCTGCCCCAGGCACCTTCTCCTCTGGGCTGGCTGGGCAGGGACAATGGGCCTGGCTGCGA GGAGGGGGCCTGGGCTGCCTTCTGCATTGCCTCGGTGACGGGAGATGGCCCCTGCCTGCT GAGGGATAGGGGAGTGGGCAGGCAGTGAGAGACACTGACAGCTGTCCCGCGGGTACAGGG CCCTGTCTGGGTGGCCAGGCCCATGTCTCGGGCCCACAGTGCGCCCCCCACCCTTGGACG GCGCCTTCTCCCTCCCCAGGTGCATGCTGCCCAGCCAGGGAGCGTGGGGGAGTTCGGGAG GGCTGGCCTACACGCCCTGGTCCAGCTGTCCCAGGTGGGGTGCTGGGCTTCAGCCCTCAG CCCAGGGCCTAGGAATCCAACTTGATCCTCCCCACACAGCAGCCAGGTTCAAATGCAGGT CCCGTAACGGAAGTGCTGCTGTGCAGCCCAGATTGGGGGGCAGGAGCCAGCAGGGCCCCC CCACCCTCTTCTCGCACCACACTGGGGAGGCAGCATTGGTTCCAGTTCCGGTTCCTGGGC TGCCCTCTCAACCCCGGCCTACAGTGGGGCCCACCCTGTGCCTTCTGATGCCACTCCCAC CCCACGCCAAGTCCCAGAGGCTTTGGGAGCGGGTGAAGGCGGTGGGTGGCGGGTGGCAGG TGCAGGCGGTGGGTGGTGGGTGTGGCAGGTGGCGGGCCCCACCGCAGGTGTCATCCCTGC GAAGCACCTGTCGCCAGCACTCAGAGCGCTCATGAGGTGCCCAGTCCCCATGTGGCCTCC TTAGTCTCCGTCCTGTGTCATGGAAGAGGTAACTGAGGCACAGAAAACTCACCAGGCCAG GCTGGGATGTGAGGTCCCTTGCTGCTCATCCCTGGCAGTCAGCAACCCTACATCTTCCCA GCTGGGCGGCCCGTGGTGGGTTCGGCACCCAGGACCCTCCGGGGTCTTGGGCTGTGGCGA GTGTGTAGGCACCCACCTGGTGTCTCTCTCCCCGCAAGGCATCTACATCCTCATCGCTGT GGGCGCTGTCATGATGTTCGTTGGCTTCCTGGGCTGCTACGGGGCCATCCAGGAATCCCA GTGCCTGCTGGGGACGGTAAGGCAGGGAGGCGGGCCTGTGCCTGGGCCGGGGAGGGGCTG GGGGCTGCGTCTGGCCCTGAGGAGGGGGCAGAGCTGGTGCTCAGGGCGGAGCCTAGAATT CTGGGGGAGGTGGCTCCTGTGCCCTGCTTTTCCCGTTTGGTTTTTAAATTAAATCCCACC GTGCTTGGTCTCCATCGTGGCCAGTTCCTACGTGACCGCTTTTCTTTGTCAAAAAATAGC CACAAATATAACAGGGAGCAAGCCTCAGCTCTGAGGCCAGCCTCGGCGTCCCGGGCACAC CGCCCCCTGTGGGAAGCCCAGGCCTGGCTGTGCCATCCAGGGCCTGGCCAGTCCAGGAAG AGGGAGCCTATGCCCGTGTCTCCAGTGGGGGAAACTGAGGCAGATCCCATGGCTCCCCCT TCCGTGGGGAGCAGGAACAAGGGGGTGGGGAAGATCAGTCAGGGGTCATGCTGCTGCACA CGCCTCCCTGGGGGCTGCAGACATCCTGGACTCACCAGCCTGTGACCCCAAACCACACGC CCCGCCCCATCCACCCCGTCCTGTGGAGCCTGGTGCCGCGTGGGGACATCCTGGGCTTTG ACGGCTCCTCCCTGCGCTGAGTTTTAGCCTCTGTGCCCCAGGGCTCCACACAAGCCGCTC ACTCCTGGTCAGGTCGTGGGCTGGTGGCTCCCACTAGCCCCTCACAGACACGCCTGCTGG GCACCTGGGTGTGTGTCCTTGGGCCCCGCCTACAGCCTGCCCTCTTTCCTCCCTCTGGCC ACTGCCCGGCTCCAGTTCTTCACCTGCCTGGTCATCCTGTTTGCCTGTGAGGTGGCCGCC GGCATCTGGGGCTTTGTCAACAAGGACCAGGTGAGCCTGGGTGTGCAGGGACAGGGTGGG GTGGGTGACGGGGGCACCCTCCTCTCCTGTCGCGGGTGGGGGTTGGGCTGACTCATGGCT TGTGGGAGCTCTTTGGGCTCTTCCTGGGTCCCACTTGCCAGGAGGATCTCCAGGGGCTTT ATGGAGGAGGCAGCATTGGGGCTGAGCACCAGGCCAGCCTCCCGTGTCCCAGCACTCCCG GGGCAGCTGAGAGTGCAGAGTCCTTGTCCTCTGGGGTCTAGCCTCGAAGCCACCCTGCCC AGGGAGAGCCTGGGAAAAGTGCGTCCGCCTGGGGCGGGGCGGGGTGGGGGCAAGGAGGGG GAGGTTCCCCCTGTGCATGTGACCGCACCCCTCCCCCAGATCGCCAAGGATGTGAAGCAG TTCTATGACCAGGCCCTACAGCAGGCCGTGGTGGATGATGACGCCAACAACGCCAAGGCT GTGGTGAAGACCTTCCACGAGACGGTGCGGCCCCGGGGGGCGAGGGCGGGGAGCAGGGCC CCGGGAACCCGGCGGGGTGTGTCTCGTCCTGGATGAATCCTGCCTACGCCCAGACCTCAG GAGCAGGAGGTGCCCTTGGGACCTCCAGGACCCCTGGTCTCAACTGGTCCTCGGGTGGGA ACCTAGTGGGCCAGGGTGGCCCAGGGTGCGGAAAGCTCTGAGCAGCGCAGCTGAGGAGGA AGAAGGCTGGCCCCTGGATGCATTCTGCAGTGGGGAGCGCTGCGTACCCCTGGCCACCTC CCCATGGGTTCCCTAGAGCCACCGTCCCCCTGGGCACATCCAGGGCTGACCTTGCACCCC TGCTCTCTGCAGCTTGACTGCTGTGGCTCCAGCACACTGACTGCTTTGACCACCTCAGTG CTCAAGAACAATTTGTGTCCCTCGGGCAGCAACATCATCAGCAACCTCTTCAAGGTGCGC GAGGCCGGTGGGGCCGCGCCTGACCCCCCGCATGTCCCGCCCCTGGGTGGGGTCCTAGGG GTGGGCAGGTCACACGGCAGCCCCACAGGGAGCGACCACACTGGGTGGCATGGCCCCTGT CAGGGCTGCTCTGCTGGGAGGGTTGGGGTGGGACCGCATCTGGCCCACGAGGAAGGCAGG CGCCCTGTGCTGCGCATTCCGGGTGAAGAAGGTGGAGGCTCTGGGGGGTGGGAACTCACC TGCACCCCCAGCTCCACGTGTGCACTCGTGGGTGTGGACGCCCCTGACAGCCTGTAGCTG GCAGGGCCTGCAGGCCATATAGTGCCCTGTGGAAGTTTCCTGCTGAGGCCTCAGTGGAAG TCGTCATCAGTGATGCTTTAGGGGTCTAGTGACACCAATGACCGTGATCTCAGTGGAAAA GGGCACAGTGTGTCCCAGGCATTTCGCGTTTATGTTAAAACGGGTGGAAGATAGCAAGCC GGCAGAGGCCGGGCCGCTGCACCCGCCTGTTCCGAGGTGGGTAGGGGGTGGGGGGCTGTT CCCAGGATTCCCCTCTACGCTTTCTGTGGTGACCACGGATTACTGCGTGACAACGGGAAG CCGGGAGCCGAGGCCCGGTCCCTGACCACGCGTGCCTGGCCACCCCTGCAGGAGGACTGC CACCAGAAGATCGATGACCTCTTCTCCGGGAAGCTGTACCTCATCGGCATTGCTGCCATC GTGGTCGCTGTGATCATGGTGAGCGGGCGGGGGCGGAGGGCCTGCTCTCTGGGCTGCCCC TTCCGCGGGGCCTTGTGCTGACTGCGCCCCCCACCACCCTCCTGCAGATCTTCGAGATGA TCCTGAGCATGGTGCTGTGCTGTGGCATCCGGAACAGCTCCGTGTACTGAGGCCCCGCAG CTCTGGCCACAGGGACCTCTGCAGTGCCCCCTAAGTGACCCGGACACTTCCGAGGGGGCC ATCACCGCCTGTGTATATAACGTTTCCGGTATTACTCTGCTACACGTAGCCTTTTTACTT TTGGGGTTTTGTTTTTGTTCTGAACTTTCCTGTTACCTTTTCAGGGCTGACGTCACATGT AGGTGGCGTGTATGAGTGGAGACGGGCCTGGGTCTTGGGGACTGGAGGGCAGGGGTCCTT CTGCCCTGGGGTCCCAGGGTGCTCTGCCTGCTCAGCCAGGCCTCTCCTGGGAGCCACTCG CCCAGAGACTCAGCTTGGCCAACTTGGGGGGCTGTGTCCACCCAGCCCGCCCGTCCTGTG GGCTGCACAGCTCACCTTGTTCCCTCCTGCCCCGGTTCGAGAGCCGAGTCTGTGGGCACT CTCTGCCTTCATGCACCTGTCCTTTCTAACACGTCGCCTTCAACTGTAATCACAACATCC TGACTCCGTCATTTAATAAAGAAGGAACATCAGGCATGCTACCAGGCCTGTGCAGTCCCT CAG OMIM ID 186845