Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CD151 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID977
Official gene symbolCD151
Full nameCD151 molecule (Raph blood group)
Aliases,GP27,MER2,PETA-3,RAPH,SFA1,TSPAN24,
Gene summaryThe protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq]
LocationChromosome: 11   Locus: 11p15.5
Gene position832952 - 838835  Map Viewer
Gene orientationplus
Gene size5884 bp
Gene sequence
OMIM ID602243