Entrez gene ID | | 977 |
Official gene symbol | | CD151 |
Full name | | CD151 molecule (Raph blood group) |
Aliases | | ,GP27,MER2,PETA-3,RAPH,SFA1,TSPAN24, |
Gene summary | | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p15.5 |
Gene position | | 832952 - 838835 Map Viewer |
Gene orientation | | plus |
Gene size | | 5884 bp |
Gene sequence |
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OMIM ID | | 602243 |
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