Entrez gene ID | | 9794 |
Official gene symbol | | MAML1 |
Full name | | mastermind-like 1 (Drosophila) |
Aliases | | ,FLJ53540,KIAA0200,Mam-1,Mam1, |
Gene summary | | This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q35 |
Gene position | | 179159851 - 179204287 Map Viewer |
Gene orientation | | plus |
Gene size | | 44437 bp |
Gene sequence |
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OMIM ID | | 605424 |