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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ARNT2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9915
Official gene symbolARNT2
Full namearyl-hydrocarbon receptor nuclear translocator 2
Aliases,KIAA0307,bHLHe1,
Gene summaryThis gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q24
Gene position80696692 - 80890278  Map Viewer
Gene orientationplus
Gene size193587 bp
Gene sequence
OMIM ID606036