Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDC25B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID994
Official gene symbolCDC25B
Full namecell division cycle 25 homolog B (S. pombe)
Aliases,-,
Gene summaryCDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq]
LocationChromosome: 20   Locus: 20p13
Gene position3776401 - 3786762  Map Viewer
Gene orientationplus
Gene size10362 bp
Gene sequence