Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MVP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9961
Official gene symbolMVP
Full namemajor vault protein
Aliases,LRP,VAULT1,
Gene summaryThis gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq]
LocationChromosome: 16   Locus: 16p13.1-p11.2
Gene position29831787 - 29859341  Map Viewer
Gene orientationplus
Gene size27555 bp
Gene sequence
OMIM ID605088