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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CASP8AP2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9994
Official gene symbolCASP8AP2
Full namecaspase 8 associated protein 2
Aliases,CED-4,FLASH,FLJ11208,KIAA1315,RIP25,
Gene summaryThis protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
LocationChromosome: 6   Locus: 6q15
Gene position90539619 - 90584155  Map Viewer
Gene orientationplus
Gene size44537 bp
Gene sequence
OMIM ID606880