Entrez gene ID | | 9994 |
Official gene symbol | | CASP8AP2 |
Full name | | caspase 8 associated protein 2 |
Aliases | | ,CED-4,FLASH,FLJ11208,KIAA1315,RIP25, |
Gene summary | | This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein. |
Location | | Chromosome: 6 Locus: 6q15 |
Gene position | | 90539619 - 90584155 Map Viewer |
Gene orientation | | plus |
Gene size | | 44537 bp |
Gene sequence |
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OMIM ID | | 606880 |
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