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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NR1H3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS GO:0008286 insulin receptor signaling pathway IEA GO:0010467 gene expression TAS GO:0010745 negative regulation of macrophage derived foam cell differentiation IC GO:0010867 positive regulation of triglyceride biosynthetic process IMP GO:0010870 positive regulation of receptor biosynthetic process IDA GO:0010875 positive regulation of cholesterol efflux IDA GO:0010875 positive regulation of cholesterol efflux IMP GO:0010887 negative regulation of cholesterol storage IMP GO:0030522 intracellular receptor mediated signaling pathway TAS GO:0032270 positive regulation of cellular protein metabolic process IMP GO:0032369 negative regulation of lipid transport IMP GO:0032376 positive regulation of cholesterol transport IDA GO:0032570 response to progesterone stimulus IDA GO:0034145 positive regulation of toll-like receptor 4 signaling pathway IDA GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor TAS GO:0042632 cholesterol homeostasis IEA GO:0042632 cholesterol homeostasis ISS GO:0042752 regulation of circadian rhythm TAS GO:0043031 negative regulation of macrophage activation IEA GO:0043031 negative regulation of macrophage activation ISS GO:0043277 apoptotic cell clearance IMP GO:0044255 cellular lipid metabolic process IEA GO:0045723 positive regulation of fatty acid biosynthetic process IMP GO:0045861 negative regulation of proteolysis IEA GO:0045893 positive regulation of transcription, DNA-dependent IMP GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IMP GO:0048550 negative regulation of pinocytosis IMP GO:0050728 negative regulation of inflammatory response IEA GO:0050728 negative regulation of inflammatory response ISS GO:0051006 positive regulation of lipoprotein lipase activity IMP GO:0055088 lipid homeostasis ISS GO:0055092 sterol homeostasis ISS GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway NAS GO:0070328 triglyceride homeostasis IEA GO:0070328 triglyceride homeostasis ISS GO:0071222 cellular response to lipopolysaccharide IDA GO:0090188 negative regulation of pancreatic juice secretion IEA GO:0090188 negative regulation of pancreatic juice secretion ISS GO:0090341 negative regulation of secretion of lysosomal enzymes IEA GO:0090341 negative regulation of secretion of lysosomal enzymes ISS GO:2000189 positive regulation of cholesterol homeostasis IDA cellular_component GO:0000790 nuclear chromatin IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IEA molecular_function GO:0003677 DNA binding TAS GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003707 steroid hormone receptor activity IEA GO:0003713 transcription coactivator activity TAS GO:0004872 receptor activity IEA GO:0004879 ligand-dependent nuclear receptor activity IEA GO:0004879 ligand-dependent nuclear receptor activity TAS GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0015485 cholesterol binding TAS GO:0032810 sterol response element binding IDA GO:0043565 sequence-specific DNA binding IEA GO:0044212 transcription regulatory region DNA binding IDA GO:0044212 transcription regulatory region DNA binding IEA GO:0046872 metal ion binding IEA GO:0046965 retinoid X receptor binding IEA GO:0046982 protein heterodimerization activity IEA

Protein-protein interaction details for NR1H3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID EDF1 Reconstituted Complex physical 12040021 EDF1 Two-hybrid physical 12040021 NR0B2 Reconstituted Complex physical 12198243 NR0B2 Affinity Capture-Western physical 12198243 NR0B2 Affinity Capture-Western physical 12198243 NR0B2 Two-hybrid physical 12198243 RXRA Reconstituted Complex physical 8621574 PPARA Reconstituted Complex physical 8621574 BARD1 Affinity Capture-Western physical 19164445 SIRT1 Affinity Capture-Western physical 17936707 UBC Affinity Capture-Western physical 17936707 LZTR1 Two-hybrid physical 20211142 SS18L1 Two-hybrid physical 20211142 NCOR1 Two-hybrid physical 12663743 ZXDC Two-hybrid physical 15604093 KAT2B Two-hybrid physical 15604093 NCOA3 Two-hybrid physical 15604093 NCOA6 Two-hybrid physical 15604093 ACTN1 Two-hybrid physical 15604093 FOXO3 Two-hybrid physical 15604093 EIF3I Two-hybrid physical 15604093 RXRA Two-hybrid physical 15604093 NRIP1 Two-hybrid physical 15604093 SRC Two-hybrid physical 15604093 NCOA3 Two-hybrid physical 15604093 NCOR1 Two-hybrid physical 15604093 RXRG Two-hybrid physical 15604093 TMEM161A Two-hybrid physical 15604093 ING3 Two-hybrid physical 15604093 RXRB Two-hybrid physical 15604093 ZXDC Two-hybrid physical 15604093 RXRB Two-hybrid physical 15604093