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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TAB1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000185 activation of MAPKKK activity IEA GO:0000187 activation of MAPK activity TAS GO:0001701 in utero embryonic development IEA GO:0002218 activation of innate immune response TAS GO:0002224 toll-like receptor signaling pathway TAS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0003007 heart morphogenesis IEA GO:0007179 transforming growth factor beta receptor signaling pathway IEA GO:0007249 I-kappaB kinase/NF-kappaB cascade TAS GO:0007254 JNK cascade TAS GO:0008063 Toll signaling pathway TAS GO:0030324 lung development IEA GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0045087 innate immune response TAS GO:0051092 positive regulation of NF-kappaB transcription factor activity TAS GO:0051403 stress-activated MAPK cascade TAS GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS cellular_component GO:0005829 cytosol TAS GO:0010008 endosome membrane TAS GO:0043234 protein complex IEA molecular_function GO:0003824 catalytic activity IEA GO:0005515 protein binding IPI GO:0008047 enzyme activator activity TAS GO:0016301 kinase activity IEA GO:0019209 kinase activator activity IEA

Protein-protein interaction details for TAB1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TAB2 Affinity Capture-MS physical 14743216 TRAF2 Affinity Capture-MS physical 14743216 MAP3K7 Affinity Capture-Western physical 14670075 TAB2 Affinity Capture-Western physical 14670075 TAB3 Affinity Capture-Western physical 14670075 MAP3K7 Affinity Capture-Western physical 14670075 TAB2 Affinity Capture-Western physical 14670075 TAB3 Affinity Capture-Western physical 14670075 MAP3K7 Affinity Capture-Western physical 12975377 SMAD7 Affinity Capture-Western physical 12589052 XIAP Two-hybrid physical 9878061 XIAP Two-hybrid physical 9878061 XIAP Affinity Capture-Western physical 9878061 SMAD6 Affinity Capture-Western physical 11737269 SMAD7 Affinity Capture-Western physical 11737269 XIAP Affinity Capture-Western physical 12048196 MAPK14 Reconstituted Complex physical 11847341 MAPK14 Affinity Capture-Western physical 11847341 ZMYND11 Affinity Capture-Western physical 9663660 ZMYND11 Affinity Capture-Western physical 9663660 ZMYND11 Two-hybrid physical 9663660 TRAF6 Affinity Capture-Western physical 10882101 TAB2 Affinity Capture-Western physical 10882101 TRAF6 Affinity Capture-Western physical 10094049 MAP3K7 Phenotypic Enhancement genetic 10094049 MAP3K7 Affinity Capture-Western physical 10838074 TRAF6 Affinity Capture-Western physical 19112497 TNF Affinity Capture-MS physical 20005846 EIF2C3 Affinity Capture-MS physical 19167051 RIPK2 Affinity Capture-Western physical 18079694 MAP3K7 Affinity Capture-Western physical 19026643 TAB3 Affinity Capture-MS physical 21903422 MAP3K7 Affinity Capture-MS physical 21903422 MORF4L1 Affinity Capture-MS physical 21903422 MORF4L2 Affinity Capture-MS physical 21903422 TAB2 Affinity Capture-MS physical 21903422 TAB2 Affinity Capture-MS physical 21903422 TAB3 Affinity Capture-MS physical 21903422 MAP3K7 Affinity Capture-MS physical 21903422 GTPBP5 Two-hybrid physical 21900206 PHACTR3 Two-hybrid physical 21900206 C9orf78 Two-hybrid physical 21900206 CARD11 Two-hybrid physical 21900206 PDCD6IP Two-hybrid physical 21900206 CASP6 Two-hybrid physical 21900206 PPP1R7 Two-hybrid physical 21900206 GIT1 Two-hybrid physical 21900206 XPO7 Two-hybrid physical 21900206 MAPK14 Two-hybrid physical 21900206 NXPH3 Two-hybrid physical 21900206 URB1 Two-hybrid physical 21900206 PHC2 Two-hybrid physical 21900206 POLR3D Two-hybrid physical 21900206 RPL10 Two-hybrid physical 21900206 ACAP3 Two-hybrid physical 21900206 SERPINA4 Two-hybrid physical 21900206 CKB Two-hybrid physical 21900206 CFL1 Two-hybrid physical 21900206 DBN1 Two-hybrid physical 21900206 MICAL1 Two-hybrid physical 21900206 KIFC2 Two-hybrid physical 21900206 MON1A Two-hybrid physical 21900206 LAP3 Two-hybrid physical 21900206 ASRGL1 Two-hybrid physical 21900206 RBX1 Two-hybrid physical 21900206 MAPKAPK5 Two-hybrid physical 21900206 POLDIP2 Two-hybrid physical 21900206 FADD Two-hybrid physical 21900206 LCMT1 Two-hybrid physical 21900206 PTPMT1 Two-hybrid physical 21900206 EPRS Two-hybrid physical 21900206 C2orf44 Two-hybrid physical 21900206 HNRNPR Two-hybrid physical 21900206 ARAP1 Two-hybrid physical 21900206 RPLP1 Two-hybrid physical 21900206 SNRNP35 Two-hybrid physical 21900206 TSSC4 Two-hybrid physical 21900206 TRPC4AP Two-hybrid physical 21900206 PRKAR1A Two-hybrid physical 21900206