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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SPTLC1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006665sphingolipid metabolic processTAS
GO:0006686sphingomyelin biosynthetic processIEA
GO:0009058biosynthetic processIEA
GO:0030148sphingolipid biosynthetic processTAS
GO:0046511sphinganine biosynthetic processIEA
GO:0046512sphingosine biosynthetic processIEA
cellular_component
GO:0005783endoplasmic reticulumIEA
GO:0005789endoplasmic reticulum membraneTAS
GO:0016020membraneIEA
GO:0016021integral to membraneIEA
GO:0017059serine C-palmitoyltransferase complexIDA
GO:0035339SPOTS complexIDA
molecular_function
GO:0004758serine C-palmitoyltransferase activityIDA
GO:0005515protein bindingIPI
GO:0016740transferase activityIEA
GO:0016746transferase activity, transferring acyl groupsIEA
GO:0016769transferase activity, transferring nitrogenous groupsIEA
GO:0030170pyridoxal phosphate bindingIEA

Protein-protein interaction details for SPTLC1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
RGS20Affinity Capture-MSphysical17353931
C20orf24Affinity Capture-MSphysical17353931
MAGED1Affinity Capture-MSphysical17353931
ORMDL3Affinity Capture-Westernphysical20182505
ATG4CAffinity Capture-MSphysical20562859
MYCAffinity Capture-MSphysical17314511
UBCAffinity Capture-MSphysical21987572