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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SIVA1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006915 apoptosis IEA GO:0006917 induction of apoptosis IDA GO:0006924 activation-induced cell death of T cells IDA GO:0008635 activation of caspase activity by cytochrome c IDA GO:0009615 response to virus ISS GO:0019987 negative regulation of anti-apoptosis IDA GO:0032088 negative regulation of NF-kappaB transcription factor activity IDA GO:0044419 interspecies interaction between organisms IEA cellular_component GO:0005634 nucleus IEA GO:0005654 nucleoplasm IDA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005739 mitochondrion IDA molecular_function GO:0001618 viral receptor activity ISS GO:0005175 CD27 receptor binding IPI GO:0005515 protein binding IPI GO:0008270 zinc ion binding IDA GO:0008656 caspase activator activity IDA GO:0046872 metal ion binding IEA

Protein-protein interaction details for SIVA1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CD27 Two-hybrid physical 9177220 CD27 Affinity Capture-Western physical 9177220 LPAR2 Reconstituted Complex physical 19293149 LPAR2 Affinity Capture-Western physical 19293149 S1PR4 Affinity Capture-Western physical 19293149 LPAR2 Affinity Capture-Western physical 19293149 CD27 Two-hybrid physical 16683188 PXMP2 Two-hybrid physical 16683188 PXMP2 Reconstituted Complex physical 16683188 TP53 Affinity Capture-Western physical 19590512 TP53 Affinity Capture-Western physical 19590512 MDM2 Affinity Capture-Western physical 19590512 MDM2 Affinity Capture-Western physical 19590512