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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PRDX3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001893 maternal placenta development IEA GO:0006979 response to oxidative stress IMP GO:0007005 mitochondrion organization IMP GO:0008284 positive regulation of cell proliferation IDA GO:0030099 myeloid cell differentiation ISS GO:0032496 response to lipopolysaccharide ISS GO:0033673 negative regulation of kinase activity IDA GO:0034614 cellular response to reactive oxygen species IMP GO:0042542 response to hydrogen peroxide IDA GO:0042744 hydrogen peroxide catabolic process IGI GO:0042744 hydrogen peroxide catabolic process IMP GO:0043066 negative regulation of apoptosis IMP GO:0043154 negative regulation of caspase activity IMP GO:0043524 negative regulation of neuron apoptosis IEA GO:0051092 positive regulation of NF-kappaB transcription factor activity IDA GO:0051881 regulation of mitochondrial membrane potential IMP cellular_component GO:0005737 cytoplasm IDA GO:0005739 mitochondrion IDA GO:0005769 early endosome IDA GO:0008385 IkappaB kinase complex IPI molecular_function GO:0004601 peroxidase activity IEA GO:0005515 protein binding IPI GO:0008022 protein C-terminus binding IPI GO:0008785 alkyl hydroperoxide reductase activity NAS GO:0016209 antioxidant activity IEA GO:0016491 oxidoreductase activity IEA GO:0019900 kinase binding IPI GO:0019901 protein kinase binding IPI GO:0042802 identical protein binding IEA GO:0043027 caspase inhibitor activity IMP GO:0051920 peroxiredoxin activity IEA

Protein-protein interaction details for PRDX3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MAGEA11 Two-hybrid physical 16189514 MAP3K13 Two-hybrid physical 12492477 MAP3K13 Affinity Capture-Western physical 12492477 MAP3K13 Affinity Capture-Western physical 12492477 IKBKB Affinity Capture-Western physical 12492477 FANCG Two-hybrid physical 17060495 FANCG Affinity Capture-Western physical 17060495 FANCG Affinity Capture-Western physical 17060495 TERF2 Affinity Capture-MS physical 20811636 H2AFX Affinity Capture-MS physical 20000738 UCHL5 Affinity Capture-MS physical 21800051 HDAC5 Affinity Capture-MS physical 21081666 NLRX1 Affinity Capture-MS physical 21903422 UBC Affinity Capture-MS physical 18781797