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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Raf1 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000165MAPKKK cascadeISO
GO:0001666response to hypoxiaISO
GO:0006468protein phosphorylationISO
GO:0006468protein phosphorylationTAS
GO:0006915apoptosisIGI
GO:0006915apoptosisIMP
GO:0007010cytoskeleton organizationIMP
GO:0007165signal transductionIEA
GO:0007243intracellular protein kinase cascadeTAS
GO:0008285negative regulation of cell proliferationISO
GO:0016310phosphorylationIEA
GO:0031333negative regulation of protein complex assemblyISO
GO:0033138positive regulation of peptidyl-serine phosphorylationISO
GO:0035556intracellular signal transductionIEA
GO:0043066negative regulation of apoptosisISO
GO:0048011nerve growth factor receptor signaling pathwayIMP
cellular_component
GO:0005626insoluble fractionISO
GO:0005737cytoplasmISO
GO:0005829cytosolTAS
GO:0005886plasma membraneISO
GO:0005886plasma membraneTAS
GO:0016020membraneIEA
GO:0031143pseudopodiumIDA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004672protein kinase activityTAS
GO:0004674protein serine/threonine kinase activityISO
GO:0004709MAP kinase kinase kinase activityISO
GO:0005057receptor signaling protein activityIEA
GO:0005515protein bindingIPI
GO:0005524ATP bindingISO
GO:0016301kinase activityIEA
GO:0016740transferase activityIEA
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA
GO:0017016Ras GTPase bindingIPI
GO:0031434mitogen-activated protein kinase kinase bindingISO
GO:0046872metal ion bindingIEA
GO:0046982protein heterodimerization activityISO

Protein-protein interaction details for Raf1 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Hras1Affinity Capture-Westernphysical16803888
Hras1Two-hybridphysical9144171
Nek10Affinity Capture-Westernphysical20956560
Nek10Affinity Capture-Westernphysical20956560
Map2k1Affinity Capture-Westernphysical20956560