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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MAP4K1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000185 activation of MAPKKK activity IC GO:0006468 protein phosphorylation IDA GO:0006950 response to stress IDA GO:0007243 intracellular protein kinase cascade IDA GO:0007257 activation of JUN kinase activity TAS GO:0018105 peptidyl-serine phosphorylation IDA cellular_component molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity TAS GO:0004674 protein serine/threonine kinase activity IDA GO:0005083 small GTPase regulator activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IDA GO:0008349 MAP kinase kinase kinase kinase activity IDA GO:0016301 kinase activity IEA

Protein-protein interaction details for MAP4K1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID GRB2 Reconstituted Complex physical 9788432 CRK Reconstituted Complex physical 9788432 CRKL Reconstituted Complex physical 9788432 BLNK Reconstituted Complex physical 11514608 BLNK Affinity Capture-Western physical 11514608 DBNL Reconstituted Complex physical 10567356 DBNL Affinity Capture-Western physical 10567356 GRAP2 Affinity Capture-Western physical 11313918 GRAP2 Reconstituted Complex physical 11313918 GRAP2 Two-hybrid physical 11313918 GRAP2 Phenotypic Enhancement genetic 11313918 GRB2 Two-hybrid physical 9346925 NCK1 Two-hybrid physical 9346925 GRB2 Reconstituted Complex physical 9346925 GRB2 Affinity Capture-Western physical 9346925 EGFR Co-fractionation physical 9346925 MAP3K7 Affinity Capture-Western physical 10224067 MAP3K11 Biochemical Activity physical 11053428 HCLS1 Affinity Capture-Western physical 10233887 GRB2 Reconstituted Complex physical 9891069 NCK1 Reconstituted Complex physical 9891069 CRK Reconstituted Complex physical 9891069 CRKL Reconstituted Complex physical 9891069 CRK Affinity Capture-Western physical 9891069 CRKL Affinity Capture-Western physical 9891069 NCK1 Affinity Capture-Western physical 11279207 CRKL Affinity Capture-Western physical 11279207 GRB2 Affinity Capture-Western physical 11279207 CRK Affinity Capture-Western physical 11279207 LAT Affinity Capture-Western physical 11279207 LAT Co-fractionation physical 11279207 PPP4C Affinity Capture-Western physical 15364934 PPP4C Affinity Capture-Western physical 15364934 PPP4C Biochemical Activity physical 15364934 UBC Affinity Capture-Western physical 15364934 UBC Affinity Capture-MS physical 16196087