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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PARK7 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006914 autophagy IEA GO:0007005 mitochondrion organization ISS GO:0007338 single fertilization IEA GO:0008344 adult locomotory behavior IEA GO:0032091 negative regulation of protein binding IDA GO:0034599 cellular response to oxidative stress IEA GO:0042493 response to drug IEA GO:0042743 hydrogen peroxide metabolic process IEA GO:0043526 neuroprotection IDA GO:0050727 regulation of inflammatory response ISS GO:0050821 protein stabilization IMP GO:0051583 dopamine uptake IEA GO:0051899 membrane depolarization IEA GO:0060081 membrane hyperpolarization IEA GO:0060548 negative regulation of cell death IDA GO:0060765 regulation of androgen receptor signaling pathway IDA GO:0070301 cellular response to hydrogen peroxide IDA GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity IEA cellular_component GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005739 mitochondrion IDA GO:0005829 cytosol IEA GO:0030424 axon IEA molecular_function GO:0003729 mRNA binding IDA GO:0004601 peroxidase activity ISS GO:0005515 protein binding IPI GO:0008233 peptidase activity IDA GO:0042803 protein homodimerization activity IDA GO:0051920 peroxiredoxin activity IEA

Protein-protein interaction details for PARK7 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID EFCAB6 Affinity Capture-Western physical 12612053 EFCAB6 Reconstituted Complex physical 12612053 EFCAB6 Two-hybrid physical 12612053 PIAS2 Two-hybrid physical 11477070 PIAS2 Reconstituted Complex physical 11477070 PIAS2 Affinity Capture-Western physical 11477070 USP19 Affinity Capture-MS physical 19615732 C19orf62 Affinity Capture-MS physical 19615732 SOD1 PCA physical 20406884 PARK2 Affinity Capture-Western physical 15525661 PARK2 Affinity Capture-Western physical 15525661 PARK7 Affinity Capture-Western physical 15525661 STUB1 Affinity Capture-Western physical 15525661 HSPA4 Affinity Capture-Western physical 15525661 PARK2 Biochemical Activity physical 17846173 PARK2 Affinity Capture-Western physical 17846173 PARK2 Reconstituted Complex physical 17846173 MTA1 Affinity Capture-Western physical 21368136 MTA1 Affinity Capture-Western physical 21368136 MTA1 Reconstituted Complex physical 21368136 PITX3 Co-localization physical 21368136 CHD4 Affinity Capture-MS physical 20127688 HDAC1 Affinity Capture-MS physical 20127688 HDAC2 Affinity Capture-MS physical 20127688 MBD3 Affinity Capture-MS physical 20127688 MTA1 Affinity Capture-MS physical 20127688 MTA2 Affinity Capture-MS physical 20127688 GATAD2B Affinity Capture-MS physical 20127688 RBBP4 Affinity Capture-MS physical 20127688 RBBP7 Affinity Capture-MS physical 20127688 HDAC1 Affinity Capture-Western physical 20127688 MTA2 Affinity Capture-Western physical 20127688 HDAC1 Affinity Capture-Western physical 20127688 TRAF6 Affinity Capture-Western physical 20634198 TRAF6 Affinity Capture-Western physical 20634198 UBC Affinity Capture-Western physical 20634198 BBS1 Affinity Capture-MS physical 21097510 CLCF1 Affinity Capture-MS physical 21097510 MTRF1 Affinity Capture-MS physical 21097510 OTUD7B Affinity Capture-MS physical 21097510 OTUD7B Affinity Capture-Western physical 21097510 OTUD7B Affinity Capture-Western physical 21097510 PPP2R1A Affinity Capture-MS physical 17540176 PPP2R1B Affinity Capture-MS physical 17540176 BCL2L1 Reconstituted Complex physical 21852238 BAX Reconstituted Complex physical 21852238 BCL2L1 Reconstituted Complex physical 21852238 BCL2L1 Affinity Capture-Western physical 21852238