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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Klf4 (Rattus norvegicus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006351transcription, DNA-dependentIDA
GO:0006357regulation of transcription from RNA polymerase II promoterISO
GO:0006366transcription from RNA polymerase II promoterISO
GO:0008285negative regulation of cell proliferationISO
GO:0009913epidermal cell differentiationIEA
GO:0009913epidermal cell differentiationISO
GO:0014067negative regulation of phosphatidylinositol 3-kinase cascadeIMP
GO:0014740negative regulation of muscle hyperplasiaIMP
GO:0019827stem cell maintenanceIEA
GO:0019827stem cell maintenanceISO
GO:0030154cell differentiationISO
GO:0031077post-embryonic camera-type eye developmentIEA
GO:0031077post-embryonic camera-type eye developmentISO
GO:0032526response to retinoic acidIEA
GO:0032526response to retinoic acidISO
GO:0042127regulation of cell proliferationISO
GO:0042221response to chemical stimulusIEA
GO:0042221response to chemical stimulusISO
GO:0045444fat cell differentiationIEA
GO:0045444fat cell differentiationISO
GO:0045595regulation of cell differentiationIEA
GO:0045595regulation of cell differentiationISO
GO:0045892negative regulation of transcription, DNA-dependentIMP
GO:0045892negative regulation of transcription, DNA-dependentISO
GO:0045892negative regulation of transcription, DNA-dependentISS
GO:0045893positive regulation of transcription, DNA-dependentISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0048662negative regulation of smooth muscle cell proliferationIDA
GO:0048662negative regulation of smooth muscle cell proliferationIMP
GO:0048730epidermis morphogenesisIEA
GO:0048730epidermis morphogenesisISO
GO:0051898negative regulation of protein kinase B signaling cascadeIMP
GO:0070373negative regulation of ERK1 and ERK2 cascadeIMP
cellular_component
GO:0000785chromatinIDA
GO:0005622intracellularIEA
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005667transcription factor complexIDA
GO:0005730nucleolusISO
molecular_function
GO:0001010sequence-specific DNA binding transcription factor recruiting transcription factor activityIEA
GO:0001010sequence-specific DNA binding transcription factor recruiting transcription factor activityISO
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIDA
GO:0001085RNA polymerase II transcription factor bindingIEA
GO:0001085RNA polymerase II transcription factor bindingISO
GO:0003676nucleic acid bindingIEA
GO:0003690double-stranded DNA bindingIDA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0003700sequence-specific DNA binding transcription factor activityISO
GO:0008134transcription factor bindingISO
GO:0008270zinc ion bindingIEA
GO:0035014phosphatidylinositol 3-kinase regulator activityIMP
GO:0043565sequence-specific DNA bindingIDA
GO:0043565sequence-specific DNA bindingISO
GO:0044212transcription regulatory region DNA bindingIDA
GO:0044212transcription regulatory region DNA bindingISO

Protein-protein interaction details for Klf4 (Rattus norvegicus)
(Information is obtained from BioGRID)
Interacting proteinExperimentTypePubMed ID
Lamc1Two-hybridphysical12034813
Lamc1Reconstituted Complexphysical12034813
Smad2Affinity Capture-Westernphysical20375011
Smad3Affinity Capture-Westernphysical20375011
Smad2Co-localizationphysical20375011