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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Klf4 (
Rattus norvegicus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0006351
transcription, DNA-dependent
IDA
GO:0006357
regulation of transcription from RNA polymerase II promoter
ISO
GO:0006366
transcription from RNA polymerase II promoter
ISO
GO:0008285
negative regulation of cell proliferation
ISO
GO:0009913
epidermal cell differentiation
IEA
GO:0009913
epidermal cell differentiation
ISO
GO:0014067
negative regulation of phosphatidylinositol 3-kinase cascade
IMP
GO:0014740
negative regulation of muscle hyperplasia
IMP
GO:0019827
stem cell maintenance
IEA
GO:0019827
stem cell maintenance
ISO
GO:0030154
cell differentiation
ISO
GO:0031077
post-embryonic camera-type eye development
IEA
GO:0031077
post-embryonic camera-type eye development
ISO
GO:0032526
response to retinoic acid
IEA
GO:0032526
response to retinoic acid
ISO
GO:0042127
regulation of cell proliferation
ISO
GO:0042221
response to chemical stimulus
IEA
GO:0042221
response to chemical stimulus
ISO
GO:0045444
fat cell differentiation
IEA
GO:0045444
fat cell differentiation
ISO
GO:0045595
regulation of cell differentiation
IEA
GO:0045595
regulation of cell differentiation
ISO
GO:0045892
negative regulation of transcription, DNA-dependent
IMP
GO:0045892
negative regulation of transcription, DNA-dependent
ISO
GO:0045892
negative regulation of transcription, DNA-dependent
ISS
GO:0045893
positive regulation of transcription, DNA-dependent
ISO
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IDA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISO
GO:0048662
negative regulation of smooth muscle cell proliferation
IDA
GO:0048662
negative regulation of smooth muscle cell proliferation
IMP
GO:0048730
epidermis morphogenesis
IEA
GO:0048730
epidermis morphogenesis
ISO
GO:0051898
negative regulation of protein kinase B signaling cascade
IMP
GO:0070373
negative regulation of ERK1 and ERK2 cascade
IMP
cellular_component
GO:0000785
chromatin
IDA
GO:0005622
intracellular
IEA
GO:0005634
nucleus
IDA
GO:0005634
nucleus
ISO
GO:0005667
transcription factor complex
IDA
GO:0005730
nucleolus
ISO
molecular_function
GO:0001010
sequence-specific DNA binding transcription factor recruiting transcription factor activity
IEA
GO:0001010
sequence-specific DNA binding transcription factor recruiting transcription factor activity
ISO
GO:0001077
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
IDA
GO:0001085
RNA polymerase II transcription factor binding
IEA
GO:0001085
RNA polymerase II transcription factor binding
ISO
GO:0003676
nucleic acid binding
IEA
GO:0003690
double-stranded DNA binding
IDA
GO:0003700
sequence-specific DNA binding transcription factor activity
IDA
GO:0003700
sequence-specific DNA binding transcription factor activity
ISO
GO:0008134
transcription factor binding
ISO
GO:0008270
zinc ion binding
IEA
GO:0035014
phosphatidylinositol 3-kinase regulator activity
IMP
GO:0043565
sequence-specific DNA binding
IDA
GO:0043565
sequence-specific DNA binding
ISO
GO:0044212
transcription regulatory region DNA binding
IDA
GO:0044212
transcription regulatory region DNA binding
ISO
Protein-protein interaction details for Klf4 (
Rattus norvegicus
)
(Information is obtained from BioGRID)
Interacting protein
Experiment
Type
PubMed ID
Lamc1
Two-hybrid
physical
12034813
Lamc1
Reconstituted Complex
physical
12034813
Smad2
Affinity Capture-Western
physical
20375011
Smad3
Affinity Capture-Western
physical
20375011
Smad2
Co-localization
physical
20375011