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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CHUK (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002011 morphogenesis of an epithelial sheet IEA GO:0002218 activation of innate immune response TAS GO:0002224 toll-like receptor signaling pathway TAS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006468 protein phosphorylation IDA GO:0006954 inflammatory response TAS GO:0006955 immune response TAS GO:0007249 I-kappaB kinase/NF-kappaB cascade TAS GO:0007252 I-kappaB phosphorylation TAS GO:0007595 lactation IEA GO:0008063 Toll signaling pathway TAS GO:0008543 fibroblast growth factor receptor signaling pathway TAS GO:0009615 response to virus TAS GO:0009653 anatomical structure morphogenesis TAS GO:0030316 osteoclast differentiation IEA GO:0033598 mammary gland epithelial cell proliferation IEA GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0042475 odontogenesis of dentine-containing tooth IEA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade TAS GO:0045087 innate immune response TAS GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0048015 phosphatidylinositol-mediated signaling TAS GO:0050852 T cell receptor signaling pathway TAS GO:0051092 positive regulation of NF-kappaB transcription factor activity TAS GO:0060749 mammary gland alveolus development IEA GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS cellular_component GO:0005634 nucleus IDA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS GO:0008385 IkappaB kinase complex TAS GO:0009898 internal side of plasma membrane ISS GO:0035631 CD40 receptor complex ISS GO:0043231 intracellular membrane-bounded organelle IDA molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IDA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0008384 IkappaB kinase activity TAS

Protein-protein interaction details for CHUK (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FANCA Two-hybrid physical 14499622 TRPC4AP Affinity Capture-Western physical 14585990 PPM1B Affinity Capture-Western physical 14585847 PPM1B Affinity Capture-Western physical 14585847 MAP3K14 Two-hybrid physical 9244310 MAP3K14 Affinity Capture-Western physical 9244310 TRAF2 Affinity Capture-Western physical 9244310 IKBKG Reconstituted Complex physical 11877453 MAP3K8 Biochemical Activity physical 10072079 MAP3K8 Affinity Capture-Western physical 10072079 NFKBIA Biochemical Activity physical 9252186 MAP3K7 Affinity Capture-Western physical 10187861 NFKB1 Affinity Capture-Western physical 10469655 IRS1 Affinity Capture-Western physical 12351658 IKBKB Affinity Capture-Western physical 9346241 NLRP4 Affinity Capture-Western physical 12093792 AKT2 Affinity Capture-Western physical 12048203 AKT2 Biochemical Activity physical 12048203 IKBKB Co-purification physical 11864612 IKBKG Affinity Capture-Western physical 11864612 CDC37 Reconstituted Complex physical 11864612 PRKDC Biochemical Activity physical 9632806 PRKDC Reconstituted Complex physical 9632806 CHUK Affinity Capture-Western physical 10755617 TRAF2 Reconstituted Complex physical 11359906 TANK Affinity Capture-Western physical 12133833 MAP3K14 Affinity Capture-Western physical 10887201 CTNNB1 Affinity Capture-Western physical 11527961 CTNNB1 Reconstituted Complex physical 11527961 IRAK1 Affinity Capture-Western physical 11096118 AKT1 Affinity Capture-Western physical 10485710 AKT1 Biochemical Activity physical 10485710 FANCA Affinity Capture-Western physical 12210728 IKBKB Co-purification physical 12210728 MAP3K11 Biochemical Activity physical 10713178 EIF2AK2 Affinity Capture-Western physical 10848580 CASP8 Affinity Capture-Western physical 11002417 NCOA3 Affinity Capture-Western physical 11971985 NCOA3 Reconstituted Complex physical 11971985 NCOA3 Biochemical Activity physical 11971985 NFKBIA Reconstituted Complex physical 9751059 IKBKAP Affinity Capture-Western physical 9751059 AKT1 Affinity Capture-Western physical 10485711 TNFAIP3 Affinity Capture-Western physical 11594795 UBE2I Biochemical Activity physical 11853669 MAP3K14 Reconstituted Complex physical 11278268 TRAF3IP2 Affinity Capture-Western physical 10962033 IKBKB Reconstituted Complex physical 10968790 IKBKB Affinity Capture-Western physical 10968790 NFKBIA Biochemical Activity physical 9346485 NFKBIB Biochemical Activity physical 9346485 IKBKB Affinity Capture-Western physical 9346485 CHUK Affinity Capture-Western physical 9346485 IKBKB Affinity Capture-Western physical 9346485 IKBKG Co-purification physical 11057907 IKBKB Co-purification physical 11057907 UBE2N Biochemical Activity physical 11057907 MAP3K7 Affinity Capture-Western physical 10094049 MAP3K14 Affinity Capture-Western physical 10094049 IKBKAP Affinity Capture-Western physical 10094049 NFKBIA Biochemical Activity physical 10094049 MAP3K14 Biochemical Activity physical 10094049 CHUK Biochemical Activity physical 11585904 IKBKB Biochemical Activity physical 11585904 TRAF2 Affinity Capture-Western physical 19150425 IKBKG Affinity Capture-Western physical 18207244 IRAK1 Affinity Capture-Western physical 18180283 CUL1 Affinity Capture-Western physical 17914462 CNTN2 Affinity Capture-Western physical 17891179 CNTN2 Affinity Capture-Western physical 17891179 TP73 Affinity Capture-Western physical 17452332 TP73 Reconstituted Complex physical 17452332 IKBKG Reconstituted Complex physical 20098747 CNTN2 Affinity Capture-Western physical 16424386 NFKB2 Affinity Capture-Western physical 16303288 EP300 Co-localization physical 19838210 PRKCQ Affinity Capture-Western physical 15802604 AKT1 Affinity Capture-Western physical 15800029 NFKB2 Affinity Capture-Western physical 15140882 RELA Biochemical Activity physical 16382138 NCOR2 Biochemical Activity physical 16382138 NFKBIA Biochemical Activity physical 12054687 CUEDC2 Affinity Capture-Western physical 18362886 CUEDC2 Two-hybrid physical 18362886 NCOR2 Biochemical Activity physical 15494311 RELA Biochemical Activity physical 15489227 HIST2H3C Affinity Capture-Western physical 17643371 HIST2H3C Reconstituted Complex physical 17643371 IKBKB Reconstituted Complex physical 9346484 IKBKB Reconstituted Complex physical 9346484 IKBKB Affinity Capture-Western physical 9751060 IKBKG Affinity Capture-Western physical 9751060 IKBKG Affinity Capture-Western physical 9751060 MAP3K7 Affinity Capture-Western physical 9742107 MAP3K7 Affinity Capture-Western physical 9742107 TNF Affinity Capture-MS physical 20005846 PRKCA Reconstituted Complex physical 10022904 PRKCI Reconstituted Complex physical 10022904 PRKCD Reconstituted Complex physical 10022904 PRKCA Affinity Capture-Western physical 10022904 PRKCI Affinity Capture-Western physical 10022904 PRKCD Affinity Capture-Western physical 10022904 PRKCA Affinity Capture-Western physical 10022904 PRKCI Affinity Capture-Western physical 10022904 PRKCD Affinity Capture-Western physical 10022904 DUSP1 Affinity Capture-Western physical 10022904 NFKBIA Biochemical Activity physical 10066434 HTT Biochemical Activity physical 20026656 COPS5 Biochemical Activity physical 19656241 IKBKG Affinity Capture-Western physical 18079694 NFKBIA Biochemical Activity physical 20932476 IKBKB Affinity Capture-Western physical 20932476 NCOA3 Affinity Capture-MS physical 16051665 IRF5 Affinity Capture-Western physical 19786094 PRKCQ Affinity Capture-Western physical 20164171 TRIM40 Affinity Capture-Western physical 21474709 TRIM40 Affinity Capture-Western physical 21474709 NEDD8 Affinity Capture-Western physical 21474709 IKBKG Affinity Capture-Western physical 19815509 CDC37 Affinity Capture-MS physical 21903422 IKBKB Affinity Capture-MS physical 21903422 IKBKG Affinity Capture-MS physical 21903422 RELA Affinity Capture-MS physical 21903422 IKBKB Affinity Capture-MS physical 21903422 IKBKG Affinity Capture-MS physical 21903422 NCOA3 Biochemical Activity physical 15383283 IKBKG Affinity Capture-Western physical 21703539