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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CLN3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000046 autophagic vacuole fusion IEA GO:0000046 autophagic vacuole fusion ISS GO:0001508 regulation of action potential IEA GO:0001508 regulation of action potential ISS GO:0001575 globoside metabolic process IMP GO:0006457 protein folding TAS GO:0006520 cellular amino acid metabolic process IEA GO:0006520 cellular amino acid metabolic process ISS GO:0006672 ceramide metabolic process IDA GO:0006678 glucosylceramide metabolic process IMP GO:0006681 galactosylceramide metabolic process IMP GO:0006684 sphingomyelin metabolic process IMP GO:0006865 amino acid transport IEA GO:0006898 receptor-mediated endocytosis IMP GO:0007034 vacuolar transport IBA GO:0007040 lysosome organization IEA GO:0007040 lysosome organization ISS GO:0007042 lysosomal lumen acidification IMP GO:0008219 cell death IEA GO:0008306 associative learning IEA GO:0008306 associative learning ISS GO:0015809 arginine transport IDA GO:0016044 cellular membrane organization IEA GO:0016044 cellular membrane organization ISS GO:0016236 macroautophagy NAS GO:0016242 negative regulation of macroautophagy IEA GO:0016242 negative regulation of macroautophagy ISS GO:0016485 protein processing IEA GO:0016485 protein processing ISS GO:0030163 protein catabolic process NAS GO:0035235 ionotropic glutamate receptor signaling pathway IEA GO:0035235 ionotropic glutamate receptor signaling pathway ISS GO:0035752 lysosomal lumen pH elevation IDA GO:0042133 neurotransmitter metabolic process IEA GO:0042133 neurotransmitter metabolic process ISS GO:0042987 amyloid precursor protein catabolic process IDA GO:0043066 negative regulation of apoptosis IMP GO:0043086 negative regulation of catalytic activity IEA GO:0043086 negative regulation of catalytic activity ISS GO:0043524 negative regulation of neuron apoptosis IEA GO:0043524 negative regulation of neuron apoptosis ISS GO:0045861 negative regulation of proteolysis IEA GO:0045861 negative regulation of proteolysis ISS GO:0050885 neuromuscular process controlling balance IEA GO:0050885 neuromuscular process controlling balance ISS GO:0051480 cytosolic calcium ion homeostasis IEA GO:0051480 cytosolic calcium ion homeostasis ISS cellular_component GO:0000139 Golgi membrane IDA GO:0005624 membrane fraction IDA GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005739 mitochondrion TAS GO:0005764 lysosome IDA GO:0005764 lysosome IEA GO:0005765 lysosomal membrane IDA GO:0005769 early endosome IDA GO:0005769 early endosome IEA GO:0005770 late endosome IEA GO:0005770 late endosome ISS GO:0005776 autophagic vacuole IEA GO:0005776 autophagic vacuole ISS GO:0005783 endoplasmic reticulum IDA GO:0005794 Golgi apparatus IDA GO:0005795 Golgi stack IDA GO:0005802 trans-Golgi network IDA GO:0005829 cytosol ISS GO:0005886 plasma membrane IDA GO:0005901 caveola IDA GO:0008021 synaptic vesicle IDA GO:0016020 membrane IEA GO:0016021 integral to membrane IDA GO:0030176 integral to endoplasmic reticulum membrane IDA GO:0043005 neuron projection IDA GO:0044433 cytoplasmic vesicle part IEA GO:0045121 membrane raft IDA molecular_function GO:0005515 protein binding IPI GO:0048306 calcium-dependent protein binding IEA GO:0051082 unfolded protein binding TAS

Protein-protein interaction details for CLN3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SBDS Two-hybrid physical 20015955 COX15 Affinity Capture-MS physical 20562859 IMMT Affinity Capture-MS physical 20562859 GCN1L1 Affinity Capture-MS physical 20562859 KIAA0368 Affinity Capture-MS physical 20562859 XPOT Affinity Capture-MS physical 20562859 PRKDC Affinity Capture-MS physical 20562859 ESYT2 Affinity Capture-MS physical 20562859 HSD17B12 Affinity Capture-MS physical 20562859 SEC61A2 Affinity Capture-MS physical 20562859 ABCD3 Affinity Capture-MS physical 20562859 SLC25A11 Affinity Capture-MS physical 20562859 RPN2 Affinity Capture-MS physical 20562859 AFG3L2 Affinity Capture-MS physical 20562859 IRAK1 Affinity Capture-MS physical 20562859 UNC45A Affinity Capture-MS physical 20562859 NUP205 Affinity Capture-MS physical 20562859 XPO1 Affinity Capture-MS physical 20562859 NUP93 Affinity Capture-MS physical 20562859 ATG7 Affinity Capture-MS physical 20562859 TRIP13 Affinity Capture-MS physical 20562859 CYC1 Affinity Capture-MS physical 20562859 DDX20 Affinity Capture-MS physical 20562859 SIGMAR1 Affinity Capture-MS physical 20562859 RIF1 Affinity Capture-MS physical 20562859 AUP1 Affinity Capture-MS physical 20562859 SLC25A10 Affinity Capture-MS physical 20562859 VDAC2 Affinity Capture-MS physical 20562859 GEMIN4 Affinity Capture-MS physical 20562859 SFXN4 Affinity Capture-MS physical 20562859 SLC25A22 Affinity Capture-MS physical 20562859 TELO2 Affinity Capture-MS physical 20562859 PHB Affinity Capture-MS physical 20562859 NPEPPS Affinity Capture-MS physical 20562859 FANCI Affinity Capture-MS physical 20562859 CCDC47 Affinity Capture-MS physical 20562859 GANAB Affinity Capture-MS physical 20562859 CKAP4 Affinity Capture-MS physical 20562859 DDOST Affinity Capture-MS physical 20562859 CAND1 Affinity Capture-MS physical 20562859 CPT1A Affinity Capture-MS physical 20562859 ILVBL Affinity Capture-MS physical 20562859 TMPO Affinity Capture-MS physical 20562859