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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CCR5 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002407 dendritic cell chemotaxis TAS GO:0006935 chemotaxis TAS GO:0006954 inflammatory response TAS GO:0006955 immune response TAS GO:0006968 cellular defense response TAS GO:0007166 cell surface receptor linked signaling pathway TAS GO:0007186 G-protein coupled receptor protein signaling pathway TAS GO:0007204 elevation of cytosolic calcium ion concentration TAS GO:0007267 cell-cell signaling TAS GO:0016032 viral reproduction TAS GO:0019059 initiation of viral infection TAS GO:0030260 entry into host cell TAS GO:0044419 interspecies interaction between organisms IEA cellular_component GO:0005737 cytoplasm TAS GO:0005768 endosome TAS GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane TAS GO:0009897 external side of plasma membrane IDA GO:0009986 cell surface IDA molecular_function GO:0003779 actin binding IDA GO:0004435 phosphatidylinositol phospholipase C activity TAS GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA GO:0004930 G-protein coupled receptor activity IEA GO:0004950 chemokine receptor activity TAS GO:0005515 protein binding IPI GO:0015026 coreceptor activity TAS GO:0016493 C-C chemokine receptor activity IDA GO:0016493 C-C chemokine receptor activity NAS

Protein-protein interaction details for CCR5 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CCL5 Affinity Capture-Western physical 14637022 ARRB1 Reconstituted Complex physical 12065593 CXCR4 Reconstituted Complex physical 12429730 CCL3 Reconstituted Complex physical 11700073 PTK2 Affinity Capture-Western physical 10384144 CCL3L1 Reconstituted Complex physical 11734558 AFP Affinity Capture-Western physical 12176010 CD4 Affinity Capture-Western physical 10816381 JAK2 Affinity Capture-Western physical 11278738 STAT3 Affinity Capture-Western physical 11350939 STAT5B Affinity Capture-Western physical 11350939 PIK3R2 Affinity Capture-Western physical 11350939 CCL5 Reconstituted Complex physical 11449371 CCL3L1 Reconstituted Complex physical 11449371 CCL5 Reconstituted Complex physical 11116158