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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Cdkn2a (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000075cell cycle checkpointISO
GO:0000079regulation of cyclin-dependent protein kinase activityIDA
GO:0000082G1/S transition of mitotic cell cycleISO
GO:0000209protein polyubiquitinationISO
GO:0001953negative regulation of cell-matrix adhesionISO
GO:0006309DNA fragmentation involved in apoptotic nuclear changeISO
GO:0006351transcription, DNA-dependentIEA
GO:0006355regulation of transcription, DNA-dependentIDA
GO:0006364rRNA processingIEA
GO:0006469negative regulation of protein kinase activityISO
GO:0006915apoptosisIEA
GO:0006917induction of apoptosisISO
GO:0006919activation of caspase activityISO
GO:0007049cell cycleIEA
GO:0007050cell cycle arrestIDA
GO:0007050cell cycle arrestISO
GO:0007568agingIMP
GO:0007569cell agingIDA
GO:0008285negative regulation of cell proliferationISO
GO:0008544epidermis developmentIMP
GO:0008637apoptotic mitochondrial changesISO
GO:0009303rRNA transcriptionIGI
GO:0010243response to organic nitrogenISO
GO:0010389regulation of G2/M transition of mitotic cell cycleISO
GO:0010468regulation of gene expressionIMP
GO:0014070response to organic cyclic compoundISO
GO:0030308negative regulation of cell growthIMP
GO:0030308negative regulation of cell growthISO
GO:0030889negative regulation of B cell proliferationIMP
GO:0031647regulation of protein stabilityIMP
GO:0031648protein destabilizationISO
GO:0032088negative regulation of NF-kappaB transcription factor activityISO
GO:0033088negative regulation of immature T cell proliferation in thymusIMP
GO:0033235positive regulation of protein sumoylationISO
GO:0033600negative regulation of mammary gland epithelial cell proliferationIMP
GO:0034393positive regulation of smooth muscle cell apoptosisIGI
GO:0035019somatic stem cell maintenanceIGI
GO:0035986senescence-associated heterochromatin focus formationISO
GO:0042326negative regulation of phosphorylationIDA
GO:0042326negative regulation of phosphorylationISO
GO:0042493response to drugISO
GO:0043517positive regulation of DNA damage response, signal transduction by p53 class mediatorIC
GO:0043517positive regulation of DNA damage response, signal transduction by p53 class mediatorISO
GO:0045736negative regulation of cyclin-dependent protein kinase activityIDA
GO:0045736negative regulation of cyclin-dependent protein kinase activityISO
GO:0045786negative regulation of cell cycleIDA
GO:0045892negative regulation of transcription, DNA-dependentISO
GO:0045893positive regulation of transcription, DNA-dependentIMP
GO:0045893positive regulation of transcription, DNA-dependentISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0046822regulation of nucleocytoplasmic transportIGI
GO:0046825regulation of protein export from nucleusISO
GO:0048103somatic stem cell divisionIMP
GO:0050821protein stabilizationISO
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityIMP
GO:0051444negative regulation of ubiquitin-protein ligase activityIDA
GO:0060058positive regulation of apoptosis involved in mammary gland involutionIMP
GO:0070534protein K63-linked ubiquitinationISO
GO:0071158positive regulation of cell cycle arrestISO
GO:0090398cellular senescenceISO
GO:0090399replicative senescenceISO
GO:2000111positive regulation of macrophage apoptosisIGI
GO:2000774positive regulation of cellular senescenceISO
cellular_component
GO:0001652granular componentIDA
GO:0005634nucleusISO
GO:0005654nucleoplasmIDA
GO:0005654nucleoplasmISO
GO:0005730nucleolusIDA
GO:0005730nucleolusISO
GO:0005737cytoplasmIDA
GO:0005737cytoplasmISO
GO:0035985senescence-associated heterochromatin focusISO
GO:0043234protein complexISO
molecular_function
GO:0002039p53 bindingISO
GO:0003677DNA bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0004861cyclin-dependent protein kinase inhibitor activityIDA
GO:0004861cyclin-dependent protein kinase inhibitor activityISO
GO:0005515protein bindingIPI
GO:0008134transcription factor bindingISO
GO:0019901protein kinase bindingISO
GO:0051059NF-kappaB bindingISO
GO:0055105ubiquitin-protein ligase inhibitor activityIDA
GO:0070215MDM2 bindingISO

Protein-protein interaction details for Cdkn2a (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Tbrg1Affinity Capture-Westernphysical17110379
Tbrg1Affinity Capture-Westernphysical17110379