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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for COL1A1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001501 skeletal system development IMP GO:0001568 blood vessel development IMP GO:0001649 osteoblast differentiation IEA GO:0001957 intramembranous ossification IEA GO:0001958 endochondral ossification IEA GO:0007411 axon guidance TAS GO:0007584 response to nutrient IEA GO:0007596 blood coagulation TAS GO:0007601 visual perception IMP GO:0007605 sensory perception of sound IMP GO:0009612 response to mechanical stimulus IEA GO:0010035 response to inorganic substance IEA GO:0010718 positive regulation of epithelial to mesenchymal transition IDA GO:0010812 negative regulation of cell-substrate adhesion IEA GO:0015031 protein transport IEA GO:0030168 platelet activation TAS GO:0030199 collagen fibril organization IMP GO:0030335 positive regulation of cell migration IDA GO:0031960 response to corticosteroid stimulus IEA GO:0032964 collagen biosynthetic process IMP GO:0034504 protein localization to nucleus IDA GO:0034505 tooth mineralization IMP GO:0042542 response to hydrogen peroxide IEA GO:0043434 response to peptide hormone stimulus IEA GO:0043589 skin morphogenesis IMP GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0048706 embryonic skeletal system development IMP GO:0050900 leukocyte migration TAS GO:0051591 response to cAMP IEA GO:0060325 face morphogenesis IEA GO:0060346 bone trabecula formation IEA GO:0060351 cartilage development involved in endochondral bone morphogenesis IEA GO:0070208 protein heterotrimerization IEA GO:0071230 cellular response to amino acid stimulus IEA GO:0071300 cellular response to retinoic acid IEA GO:0071363 cellular response to growth factor stimulus IEA GO:0090263 positive regulation of canonical Wnt receptor signaling pathway IDA cellular_component GO:0005576 extracellular region TAS GO:0005581 collagen IEA GO:0005584 collagen type I IMP GO:0005615 extracellular space IDA GO:0005737 cytoplasm IEA GO:0005886 plasma membrane TAS GO:0031012 extracellular matrix IDA molecular_function GO:0005201 extracellular matrix structural constituent IEA GO:0005515 protein binding IPI GO:0042802 identical protein binding IDA GO:0048407 platelet-derived growth factor binding IDA

Protein-protein interaction details for COL1A1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID IGFBP3 Two-hybrid physical 12735930 TXN Two-hybrid physical 12099690 IGFBP3 Co-purification physical 12735930 IGFBP3 Affinity Capture-Western physical 12735930 ITGA2 Co-purification physical 2156854 ITGB1 Co-purification physical 2156854 NID1 Reconstituted Complex physical 9733643 NID2 Reconstituted Complex physical 9733643 SPARC Reconstituted Complex physical 2745554 PRELP Reconstituted Complex physical 11847210 PKD1 Reconstituted Complex physical 11752017 VWF Co-fractionation physical 3490481 VWF Reconstituted Complex physical 3490481 TXN Reconstituted Complex physical 12099690 THBS1 Reconstituted Complex physical 3571333 MMP2 Reconstituted Complex physical 11368514 COL7A1 Reconstituted Complex physical 9169408 MATN2 Reconstituted Complex physical 12180907 MAG Reconstituted Complex physical 2446864