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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Dvl2 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001843neural tube closureIMP
GO:0001934positive regulation of protein phosphorylationISO
GO:0003007heart morphogenesisIGI
GO:0006366transcription from RNA polymerase II promoterISO
GO:0007275multicellular organismal developmentIEA
GO:0007379segment specificationIMP
GO:0007507heart developmentIMP
GO:0016055Wnt receptor signaling pathwayIDA
GO:0016055Wnt receptor signaling pathwayNAS
GO:0021535cell migration in hindbrainIBA
GO:0022007convergent extension involved in neural plate elongationIGI
GO:0022007convergent extension involved in neural plate elongationIMP
GO:0034613cellular protein localizationIDA
GO:0035282segmentationIGI
GO:0035556intracellular signal transductionIEA
GO:0035567non-canonical Wnt receptor signaling pathwayISO
GO:0043507positive regulation of JUN kinase activityIDA
GO:0043507positive regulation of JUN kinase activityISO
GO:0044340canonical Wnt receptor signaling pathway involved in regulation of cell proliferationISO
GO:0045893positive regulation of transcription, DNA-dependentIBA
GO:0045893positive regulation of transcription, DNA-dependentISO
GO:0046328regulation of JNK cascadeIBA
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityISO
GO:0060029convergent extension involved in organogenesisIGI
GO:0060070canonical Wnt receptor signaling pathwayIDA
GO:0060070canonical Wnt receptor signaling pathwayIGI
GO:0060070canonical Wnt receptor signaling pathwayIMP
GO:0060070canonical Wnt receptor signaling pathwayISO
GO:0060071Wnt receptor signaling pathway, planar cell polarity pathwayIGI
GO:0060071Wnt receptor signaling pathway, planar cell polarity pathwayISO
GO:0061098positive regulation of protein tyrosine kinase activityIGI
GO:0090103cochlea morphogenesisIGI
GO:0090179planar cell polarity pathway involved in neural tube closureIGI
GO:0090179planar cell polarity pathway involved in neural tube closureIMP
cellular_component
GO:0005622intracellularIEA
GO:0005625soluble fractionNAS
GO:0005634nucleusIMP
GO:0005737cytoplasmIDA
GO:0005737cytoplasmISO
GO:0005856cytoskeletonNAS
GO:0005886plasma membraneIDA
GO:0005886plasma membraneIGI
GO:0005938cell cortexIBA
GO:0005938cell cortexISO
GO:0016020membraneIEA
GO:0030136clathrin-coated vesicleIDA
GO:0031410cytoplasmic vesicleIEA
GO:0044444cytoplasmic partISO
GO:0045177apical part of cellIDA
molecular_function
GO:0004871signal transducer activityIEA
GO:0005109frizzled bindingIBA
GO:0005109frizzled bindingIPI
GO:0005109frizzled bindingISO
GO:0005515protein bindingIPI
GO:0019904protein domain specific bindingIPI
GO:0042802identical protein bindingISO

Protein-protein interaction details for Dvl2 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
AgrnPhenotypic Suppressiongenetic12165471
SrcAffinity Capture-Westernphysical19920076
HckAffinity Capture-Westernphysical19920076
Grb2Affinity Capture-Westernphysical19920076
CrkAffinity Capture-Westernphysical19920076
SrcAffinity Capture-Westernphysical19920076
HckAffinity Capture-Westernphysical19920076
SrcBiochemical Activityphysical19920076
Csnk1eCo-localizationphysical17606995
Vangl2Synthetic Lethalitygenetic16571627
Dvl1Synthetic Lethalitygenetic16571627
Vangl2Phenotypic Enhancementgenetic16116426
Dvl1Phenotypic Enhancementgenetic16116426
Dvl1Phenotypic Enhancementgenetic19008950
Dvl3Synthetic Lethalitygenetic19008950
Axin1Affinity Capture-Westernphysical15579909
Axin1Affinity Capture-Westernphysical15579909