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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ADORA2B (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity TAS GO:0002882 positive regulation of chronic inflammatory response to non-antigenic stimulus IEA GO:0006968 cellular defense response TAS GO:0007186 G-protein coupled receptor protein signaling pathway TAS GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway IEA GO:0007190 activation of adenylate cyclase activity TAS GO:0007254 JNK cascade TAS GO:0007588 excretion TAS GO:0008284 positive regulation of cell proliferation IEA GO:0008285 negative regulation of cell proliferation IEA GO:0010575 positive regulation vascular endothelial growth factor production IEA GO:0010701 positive regulation of norepinephrine secretion IEA GO:0010893 positive regulation of steroid biosynthetic process IEA GO:0030819 positive regulation of cAMP biosynthetic process IEA GO:0030828 positive regulation of cGMP biosynthetic process IEA GO:0031284 positive regulation of guanylate cyclase activity IEA GO:0031668 cellular response to extracellular stimulus IEA GO:0032722 positive regulation of chemokine production IEA GO:0032755 positive regulation of interleukin-6 production IEA GO:0032966 negative regulation of collagen biosynthetic process IEA GO:0043306 positive regulation of mast cell degranulation IEA GO:0045765 regulation of angiogenesis IEA GO:0045909 positive regulation of vasodilation IEA GO:0060087 relaxation of vascular smooth muscle IEA cellular_component GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane TAS GO:0009986 cell surface IEA molecular_function GO:0001609 adenosine receptor activity, G-protein coupled IEA GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA

Protein-protein interaction details for ADORA2B (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SLC9A3R2 Affinity Capture-Western physical 12080047 EZR Affinity Capture-Western physical 12080047