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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Esr1 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001547antral ovarian follicle growthIMP
GO:0002064epithelial cell developmentIMP
GO:0006351transcription, DNA-dependentIEA
GO:0006355regulation of transcription, DNA-dependentIDA
GO:0008209androgen metabolic processIMP
GO:0008584male gonad developmentIMP
GO:0016049cell growthNAS
GO:0030518steroid hormone receptor signaling pathwayISO
GO:0030520estrogen receptor signaling pathwayISO
GO:0030522intracellular receptor mediated signaling pathwayIDA
GO:0032355response to estradiol stimulusISO
GO:0042981regulation of apoptosisIMP
GO:0043401steroid hormone mediated signaling pathwayISO
GO:0043526neuroprotectionISO
GO:0043627response to estrogen stimulusISO
GO:0045742positive regulation of epidermal growth factor receptor signaling pathwayISO
GO:0045839negative regulation of mitosisNAS
GO:0045885positive regulation of survival gene product expressionISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterIMP
GO:0048146positive regulation of fibroblast proliferationIMP
GO:0048386positive regulation of retinoic acid receptor signaling pathwayISO
GO:0060011Sertoli cell proliferationISO
GO:0060065uterus developmentIGI
GO:0060068vagina developmentIGI
GO:0060523prostate epithelial cord elongationIMP
GO:0060527prostate epithelial cord arborization involved in prostate glandular acinus morphogenesisIMP
GO:0060687regulation of branching involved in prostate gland morphogenesisIMP
GO:0060745mammary gland branching involved in pregnancyIMP
GO:0060749mammary gland alveolus developmentIMP
GO:0060750epithelial cell proliferation involved in mammary gland duct elongationIMP
GO:0070374positive regulation of ERK1 and ERK2 cascadeISO
GO:0071391cellular response to estrogen stimulusIMP
cellular_component
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005737cytoplasmIDA
GO:0005737cytoplasmISO
GO:0005886plasma membraneISO
GO:0030315T-tubuleISO
GO:0043005neuron projectionISO
GO:0043195terminal buttonISO
GO:0043204perikaryonISO
GO:0043234protein complexISO
GO:0044429mitochondrial partISO
GO:0048471perinuclear region of cytoplasmISO
molecular_function
GO:0003677DNA bindingISO
GO:0003682chromatin bindingIDA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0003707steroid hormone receptor activityISO
GO:0004872receptor activityIEA
GO:0004879ligand-dependent nuclear receptor activityIDA
GO:0005496steroid bindingISO
GO:0005515protein bindingIPI
GO:0008013beta-catenin bindingISO
GO:0008134transcription factor bindingIPI
GO:0008270zinc ion bindingIEA
GO:0008289lipid bindingIEA
GO:0019899enzyme bindingISO
GO:0030284estrogen receptor activityISO
GO:0031798type 1 metabotropic glutamate receptor bindingISO
GO:0032403protein complex bindingISO
GO:0034056estrogen response element bindingISO
GO:0042562hormone bindingISO
GO:0043565sequence-specific DNA bindingIEA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for Esr1 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Smarce1Reconstituted Complexphysical12145209
JunAffinity Capture-Westernphysical19605792
JunAffinity Capture-Westernphysical19605792
Ncoa2Two-hybridphysical20211142
Pou4f1Two-hybridphysical20211142
Pou4f2Two-hybridphysical20211142
Kdm4bAffinity Capture-Westernphysical21445275
Kdm4bAffinity Capture-Westernphysical21445275
Kdm4aAffinity Capture-Westernphysical21445275
Kdm4cAffinity Capture-Westernphysical21445275