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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Esr2 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterISO
GO:0001541ovarian follicle developmentIMP
GO:0001662behavioral fear responseISO
GO:0001764neuron migrationIMP
GO:0006351transcription, DNA-dependentIEA
GO:0006355regulation of transcription, DNA-dependentIEA
GO:0007420brain developmentIMP
GO:0007611learning or memoryISO
GO:0008285negative regulation of cell proliferationIGI
GO:0030518steroid hormone receptor signaling pathwayISO
GO:0030520estrogen receptor signaling pathwayIMP
GO:0030520estrogen receptor signaling pathwayISO
GO:0033574response to testosterone stimulusISO
GO:0042127regulation of cell proliferationIMP
GO:0043065positive regulation of apoptosisIMP
GO:0043401steroid hormone mediated signaling pathwayISO
GO:0043526neuroprotectionISO
GO:0045742positive regulation of epidermal growth factor receptor signaling pathwayISO
GO:0045885positive regulation of survival gene product expressionISO
GO:0045893positive regulation of transcription, DNA-dependentISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0048521negative regulation of behaviorISO
GO:0050680negative regulation of epithelial cell proliferationIMP
GO:0050680negative regulation of epithelial cell proliferationISO
GO:0060011Sertoli cell proliferationISO
GO:0060065uterus developmentIGI
GO:0060068vagina developmentIGI
GO:0060740prostate gland epithelium morphogenesisIMP
GO:0060743epithelial cell maturation involved in prostate gland developmentIMP
GO:0060766negative regulation of androgen receptor signaling pathwayIMP
GO:0070374positive regulation of ERK1 and ERK2 cascadeISO
cellular_component
GO:0005634nucleusISO
GO:0005737cytoplasmISO
GO:0005739mitochondrionISO
GO:0005886plasma membraneISO
GO:0043005neuron projectionISO
GO:0043204perikaryonISO
GO:0048471perinuclear region of cytoplasmISO
molecular_function
GO:0003677DNA bindingIDA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0003707steroid hormone receptor activityISO
GO:0004872receptor activityIEA
GO:0005496steroid bindingISO
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GO:0008289lipid bindingIEA
GO:0019899enzyme bindingISO
GO:0030284estrogen receptor activityISO
GO:0034056estrogen response element bindingISO
GO:0042562hormone bindingISO
GO:0043565sequence-specific DNA bindingISO
GO:0046872metal ion bindingIEA

Protein-protein interaction details for Esr2 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Rbm39Two-hybridphysical20211142
ApcPhenotypic Enhancementgenetic18464259